Cochrane · systematic review · CD010480
HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass
Lewicki, M, Ng, I, Schneider, AG · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
5
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 0 · 0%Very low 3 · 50%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adults undergoing surgery requiring cardiac bypass
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Acute kidney injury | RR 0.76 [0.46, 1.28] | 5 studies · 467 participants | Low |
Serum creatinine | no estimate extracted | 2 studies · 195 participants | Low |
Renal replacement therapy | RR 0.8 [0.23, 2.81] | 2 studies · 251 participants | Very low |
Mortality | RR 3.86 [0.43, 34.4] | 5 studies · 381 participants | Very low |
Adverse events | RR 1.13 [1.47, 2.68] | 1 study · 140 participants | Very low |
ICU ‐ intensive care unit | no estimate extracted | NR | No studies |