Cochrane · systematic review · CD010909
Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department
Kew, KM, Kirtchuk, L, Michell, CI · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 3 · 42.9%Moderate 2 · 28.6%High 2 · 28.6%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
IV MgSO4 for treating adults with acute asthma in the emergency department
Population: adults with acute asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Hospital admissions | OR 0.75 [0.6, 0.92] | 11 studies · 1769 participants | High |
Intensive care unit (ICU) admissions | OR 2.03 [0.7, 5.89] | 1 study · 752 participants | Low Downgraded: imprecision |
Length of hospital stay (days) | no estimate extracted | 3 studies · 949 participants | Low Downgraded: risk of bias |
ED treatment duration (minutes) | no estimate extracted | 1 study · 96 participants | Low Downgraded: risk of bias, imprecision |
FEV1 (% predicted) | no estimate extracted | 4 studies · 523 participants | High |
PEF (L/min) | no estimate extracted | 8 studies · 1460 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Respiratory rate (breaths/min) | no estimate extracted | 4 studies · 1195 participants | Moderate Downgraded: inconsistency |