Cochrane · systematic review · CD006616
N‐acetylcysteine for sepsis and systemic inflammatory response in adults
Szakmany, T, Hauser, B, Radermacher, P · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: Adult patients with SIRS or sepsis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality 30‐day | RR 1.07 [0.8, 1.43] | 11 studies · 930 participants | Moderate |
Length of stay on the intensive care unit (days) | no estimate extracted | 19 studies · 1309 participants | Moderate |
Duration of mechanical ventilation (days) | no estimate extracted | 9 studies · 423 participants | Moderate |
Incidence of new organ failure | RR 1.01 [0.8, 1.27] | 12 studies · 1224 participants | Moderate |