Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

567 questions · 599 findings · 114 reviews

No studies found 136 · 22.7%GRADE not reported 45 · 7.5%Very low 166 · 27.7%Low 152 · 25.4%Moderate 75 · 12.5%High 25 · 4.2%

Cuffed vs uncuffed tubes

Need for intensive care unit (ICU) admission to treat post extubation stridor (as defined by the trial authors) · Children up to eight years undergoing general anaesthesia

It is very uncertain whether cuffed changes need for intensive care unit (ICU) admission to treat post… compared with uncuffed tubes (very low certainty).

1 finding from 1 review

Amnioinfusion vs no amnioinfusion

Perinatal death or severe morbidity · pregnant women with confirmed or suspected chorioamnionitis

The review found no eligible studies for this question.

1 finding from 1 review

Reduced number of antenatal care visits/goal‐oriented vs standard antenatal care visits

Admission to neonatal intensive care unit · Pregnant women at low risk of complications

Reduced number of antenatal care visits/goal‐oriented showed no clear difference in neonatal intensive care unit admission compared with standard antenatal care visits (moderate certainty).

1 finding from 1 review

All routine Doppler ultrasound vs no Doppler ultrasound

Admission to neonatal special care unit or intensive care unit · Pregnant women in unselected or low‐risk populations.

All routine Doppler ultrasound showed no clear difference in neonatal admission to special care baby unit/neonatal intensive care… compared with no Doppler ultrasound (moderate certainty).

1 finding from 1 review

Group antenatal care vs individual antenatal care (adjusted data)

Neonatal admission to NICU · pregnant women accessing prenatal care

Group antenatal care showed no clear difference in neonatal intensive care unit (NICU) admission (admission of baby to… compared with individual antenatal care (adjusted data) (moderate certainty).

1 finding from 1 review

Traditional antenatal CTG vs no antenatal CTG (women at increased risk of complication)

Admission to neonatal special care unit or intensive care unit · Pregnant women with/without complications

Traditional antenatal CTG showed no clear difference in admission to neonatal special care unit or intensive care unit compared with no antenatal CTG (women at increased risk of complication) (low certainty).

1 finding from 1 review

Planned early birth vs expectant management

Significant maternal morbidity one or more of the following: significant postpartum haemorrhage requiring blood transfusion; maternal admission to intensive care unit; uterine rupture; hysterectomy · pregnant women with a term suspected compromised baby

Planned early delivery showed no clear difference in significant maternal morbidity one or more of the following:… compared with expectant management (low certainty).

1 finding from 1 review