Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

436 questions · 451 findings · 96 reviews · Headline outcomes only

No studies found 31 · 6.9%GRADE not reported 17 · 3.8%Very low 149 · 33%Low 130 · 28.8%Moderate 103 · 22.8%High 21 · 4.7%

Intervention not reported

Immediate postoperative anxiety (VAS) VAS (0 to 100 mm) measured approximately 90 minutes after surgery or in recovery room 0: no anxiety 100: maximum anxiety possible · patients undergoing elective surgery
1 finding from 1 review

Intervention not reported

Immediate postoperative anxiety (VAS) VAS (0 to 100 mm) measured after surgery, in recovery, or at discharge from recovery room 0: no anxiety 100: maximum anxiety possible · patents undergoing elective surgery
1 finding from 1 review

rHuEPO with iron vs control treatment with or without iron

Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO high (500 to 600 IU/kg BW) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia
1 finding from 1 review

rHuEPO with iron vs control treatment with or without iron

Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO low (150 to 300 IU/kg BW) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia
1 finding from 1 review

Intervention not reported

Complete resolution of symptoms (proportion of patients with 'immediate and persistent resolution of symptoms' from the point of surgery/randomisation up to end of study · children with PFAPA

The intervention showed no clear difference in complete resolution of symptoms (proportion of patients with… (moderate certainty).

1 finding from 1 review

Herbal treatment vs placebo

Participant‐reported pain relief of 30% or greater · adults with neuropathic pain

It is very uncertain whether herbal treatment changes participant‐reported pain relief of 30% or greater Immediately… compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects Defined as deaths, hospitalisations, congenital abnormalities and life‐threatening conditions requiring an immediate hospital visit Assessed at 12 and 18 months of age · children aged 6 to 23 months

The intervention showed no clear difference in adverse effects Defined as deaths, hospitalisations, congenital… (moderate certainty).

1 finding from 1 review

Intervention not reported

4a. Procedural crying (during and immediately after the vaccination procedure) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP combination vaccine
1 finding from 1 review

Intervention not reported

4a. Procedural crying (during and immediately after the vaccination procedure) (not measured) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

4a. Procedural crying (during and immediately after the vaccination procedure) (not measured) · infants aged approximately 2 to 6 months undergoing vaccination in the anterolateral thigh with a DTwP‐Hib vaccine

The review found no eligible studies for this question.

1 finding from 1 review