Question · asked by 1 review

rHuEPO with iron vs control treatment with or without iron: Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO high (500 to 600 IU/kg BW)

Population
adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia
Intervention
rHuEPO with iron
Comparison
control treatment with or without iron
Outcome
Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO high (500 to 600 IU/kg BW)

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
rHuEPO with iron vs control treatment with or without iron
Subgroup Hb concentration immediately prior to surgery (g/dL) rHuEPO high (500 to 600 IU/kg BW) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia
Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults… (2020) · Cochrane Headline outcomes only
no estimate extracted3 studies · 852 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing non‐cardiac surgery
2020 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.