Intervention not reported
Difference in summary specificity (NMA, Analysis 2)
1 finding from 1 review
Development of >=1 new carious lesion (caries incidence) · Children with sound primary molars, aged 2-4 years (municipal dental clinics or hospital paediatric clinics, Denmark)
It is very uncertain whether autopolymerised sealant changes development of >=1 new carious lesion (caries incidence) compared with light polymerised sealant (very low certainty).
1 finding from 1 review
Contribution to total daily fluoride intake · children
For children in poor-fluoridated areas, the mean contribution was 45% (SD 28%).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Herbal mouthrinse showed no clear difference in presence of dry socket compared with chlorhexidine 0.2% mouthrinse; GRADE not reported.
1 finding from 1 review
Pain during the procedure (primary analysis) · Children (3-13 years) with dentine caries in primary teeth, no pulpal involvement
The reported estimate for procedural pain with ART versus conventional treatment was inconclusive (ungraded).
1 finding from 1 review
Patient discomfort during treatment (anxiety scale) · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
One study found no significant difference in patient discomfort between SDF and ART (p = 0.15; ungraded).
1 finding from 1 review
Angular cheilitis (WHO clinical stage 2) · Children or adolescents
No significant difference in angular cheilitis prevalence between CLWH and healthy controls (pooled OR 1.95, 95% CI 0.16 to 23.65).
1 finding from 1 review
Restoration failure · Children (2-9 years) with caries in posterior primary teeth
Multi-surface ART restorations had a high reported mean annual failure rate (17%; ungraded).
1 finding from 1 review
Number of caries in primary teeth (dt index) · School children, primary school in Saudi Arabia
It is very uncertain whether referral to a specific dental treatment facility changes number of caries in primary teeth (dt index) compared with generic advice letter to see a dentist (very low certainty).
1 finding from 1 review
Sensitivity for detection of enamel caries · Asymptomatic children or adults suspected of enamel caries (clinical studies); extracted teeth (in vitro studies)
Transillumination and OCT had a summary sensitivity of 0.76 (95% CrI 0.63, 0.86) for detecting enamel caries; low certainty.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Acellular dermal matrix led to lower presence of dry socket compared with control; GRADE not reported.
1 finding from 1 review
Intervention not reported
Difference in summary specificity (NMA, Analysis 2)
1 finding from 1 review
All‐cause death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all-cause death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Change in data on economics and quality of life · Residents of nursing homes and other long-term care facilities
Professional oral care led to higher change in data on economics and quality of life compared with usual oral care; GRADE not reported.
1 finding from 1 review
Restoration survival · Children with occlusoproximal caries in primary teeth
The reported pooled ART success estimate was 1.04.
1 finding from 1 review
Dental caries prevalence · European adolescents aged 17 years
Pooled caries prevalence was 0.84.
1 finding from 1 review
Good brushing habits prevalence (among children with caries) · Children with dental caries (deciduous and/or permanent dentition) in low- and middle-income countries
About 57% of children with caries in LMICs had good brushing habits (pooled prevalence 0.569, 95% CI 0.354 to 0.771; 7 studies; very high heterogeneity; not GRADE-rated).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
It is very uncertain whether platelet rich plasma changes presence of dry socket compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
Conventional GIC had an annual failure rate of 7.6-16.6% (2 RCTs) and failed more than amalgam in one trial; low quality of evidence (ungraded).
1 finding from 1 review
Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in psychological distress at follow-up compared with usual care, waiting list or no treatment (control) (low certainty).
2 findings from 1 review