Question · asked by 1 review

Autologous platelet‐rich plasma vs placebo or no treatment: Presence of dry socket

Population
Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Intervention
Autologous platelet‐rich plasma
Comparison
placebo or no treatment
Outcome
Presence of dry socket

It is very uncertain whether platelet rich plasma changes presence of dry socket compared with placebo or no treatment (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Platelet rich plasma vs Placebo or no treatment
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars) · Follow-up: median 7 days
It is very uncertain whether platelet rich plasma changes presence of dry socket compared with placebo or no treatment (very low certainty).
Local interventions for the management of alveolar osteitis (dry socket) (2022) · Cochrane All outcomes
RR 0.51 [0.19, 1.33]2 studies · 127 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Local interventions for the management of alveolar osteitis (dry socket)
2022 · Cochrane All outcomes
2021-09Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.