Early childhood caries (ECC) · Children aged 0-5 years in North Africa
Having one sibling was associated with higher odds of ECC (OR 3.32).
1 finding from 1 review
OR 3.32 [1.15, 9.54]
1 study
GRADE not reported
Adequate periodontal tissue · Children receiving dental restorations (aged 4-11 years; primary teeth; Class I/II/V cavities)
Uncertain whether IRR and CR differ in periodontal tissue outcomes (low certainty; downgraded for very serious inconsistency).
1 finding from 1 review
Dental caries · Children aged 2 to 8 years
The review reported a lower odds ratio at maternal prenatal vitamin D ≤50 nmol/L than at ≤35 nmol/L, without a numeric value in the available sources.
1 finding from 1 review
Early childhood caries (ECC) · Preschool children (<6 years)
After excluding one study, nocturnal breastfeeding was associated with higher ECC risk (RR 3.05, 95% CI 2.40 to 3.87; I²=33%).
1 finding from 1 review
Early childhood caries (ECC) · Children aged <6 years
No significant association between cesarean vs vaginal delivery and ECC among America/Canada/Brazil studies (OR 1.11, 95% CI 0.70-1.76).
17 findings from 1 review
OR 1.11 [0.70, 1.76]
5 studies
GRADE not reported
OR 0.86 [0.54, 1.38]
11 studies
GRADE not reported
OR 0.93 [0.65, 1.33]
12 studies
GRADE not reported
Show 14 more findings
Dental caries prevalence · Children aged 2 to 8 years
The review reported 44% dental caries prevalence among children of mothers with low prenatal vitamin D.
2 findings from 1 review
Early childhood caries (ECC) · Children aged ≤6 years (early childhood)
RETRACTED. Among studies before 2017, oral C. albicans presence was associated with higher odds of ECC (OR 4.89, 95% CI 2.79-8.58); ungraded subgroup from a retracted review.
16 findings from 1 review
Show 13 more findings
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Study quality (NOS): good
OR 5.32 [2.89, 9.80]
7 studies
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Sample collection: saliva
OR 4.70 [2.44, 9.09]
7 studies
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Overall (all 22 studies, random-effects)
OR 4.42 [3.14, 6.24]
22 studies · 3301 participants
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Sample size: >=100 (Table 6; abstract text erroneously states '>=1000')
OR 4.65 [2.57, 8.42]
6 studies
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Sample collection: oral swab
OR 9.55 [2.17, 42.01]
2 studies
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Study design: case-control
OR 5.30 [1.72, 16.31]
2 studies · 708 participants
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Region: Asia
OR 3.62 [2.53, 5.20]
12 studies · 2347 participants
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Sample size: <100 (Table 6; abstract text erroneously states '<1000')
OR 4.35 [2.75, 6.89]
16 studies
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Time period: 2018 and later
OR 4.17 [2.62, 6.64]
12 studies
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Study design: cross-sectional
OR 4.30 [2.92, 6.33]
20 studies · 2593 participants
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Study quality (NOS): moderate
OR 3.84 [2.24, 6.57]
11 studies
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Region: America/Canada/Brazil/Chile
OR 3.98 [1.14, 13.87]
5 studies · 319 participants
GRADE not reported
RETRACTED: Investigating the association between Candida albicans and early childhood dental caries: A comprehensive… 2024 All outcomesExposure and outcome assessed concurrently (observational); children aged ≤6 years · Children aged ≤6 years; multiple countries (Asia, Europe, Americas); dental/clinical and community settings · Study quality (NOS): low
OR 5.14 [2.12, 12.48]
4 studies
GRADE not reported
Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy
For prenatal vitamin D measured across gestational weeks 6-38, the OR of dental caries was 1.32 (no CI reported); ungraded.
3 findings from 1 review
Early childhood caries (ECC) · Preschool children (<6 years)
After excluding Peres et al. (2017), breastfeeding for less than 24 months was associated with fewer caries (RR 0.49, 95% CI 0.39 to 0.62; I²=6%).
1 finding from 1 review
Early childhood caries (ECC) · Preschool children (<6 years)
After excluding five studies, breastfeeding was associated with lower ECC risk in cohort studies (RR 0.82, 95% CI 0.71 to 0.95; I²=0%).
1 finding from 1 review
Early childhood caries (ECC) · Children with average age >3 years
No significant association between cesarean vs vaginal delivery and ECC among children with average age >3 years (OR 1.24, 95% CI 0.89-1.71).
1 finding from 1 review
OR 1.24 [0.89, 1.71]
14 studies
GRADE not reported
Dental caries · Children aged 2 to 8 years
The review reported an OR of 1.32 when prenatal vitamin D was measured at 6 to 38 gestational weeks.
2 findings from 1 review
Dental caries in children · Children aged 6 to 8 years whose mothers' prenatal vitamin D status was assessed
In the single study of children aged 6-8 years, the association was not statistically significant (OR 1.07, 95% CI 0.84-1.30); ungraded.
1 finding from 1 review
Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and… 2024 All outcomesPrenatal exposure; dental caries at 6 to 8 years · Observational pregnancy/birth-cohort studies (one cross-sectional), mostly in developed countries (USA, Canada, Japan, Australia, Spain, Netherlands, Poland, New Zealand, Turkey) · Children's age subgroup: 6 to 8 years
OR 1.07 [0.84, 1.30]
1 study
GRADE not reported
Dental caries in children · Infants and children (aged about 2 to 8 years) whose mothers' vitamin D status was assessed during pregnancy
For prenatal vitamin D measured across gestational weeks 24-38, the OR of dental caries was 1.30 (no CI reported); ungraded.
1 finding from 1 review
Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and… 2024 All outcomesMaternal 25(OH)D measured at gestational weeks 24 to 38 · Observational pregnancy/birth-cohort studies (one cross-sectional), mostly in developed countries (USA, Canada, Japan, Australia, Spain, Netherlands, Poland, New Zealand, Turkey) · Gestational-age subgroup: weeks 24 to 38
OR 1.30 [1.15, 1.45]
4 studies
GRADE not reported
Lactobacillus spp. mean levels/counts · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
No significant difference in Lactobacillus spp. presence was reported; GRADE was not reported.
1 finding from 1 review
Early childhood caries (ECC) · Preschool children (<6 years)
After excluding two studies, breastfeeding for less than 18 months was associated with fewer dental caries (RR 0.26, 95% CI 0.16 to 0.42; I²=0%).
1 finding from 1 review
Early childhood caries (ECC) · Children with average age ≤3 years
No significant association between cesarean vs vaginal delivery and ECC among children with average age ≤3 years (OR 0.86, 95% CI 0.67-1.10).
1 finding from 1 review
OR 0.86 [0.67, 1.10]
10 studies
GRADE not reported
Early childhood caries (ECC) · Preschool children (<6 years)
After excluding three studies, breastfeeding for less than 12 months was associated with lower dental caries risk (RR 0.70, 95% CI 0.62 to 0.80; I²=0%).
1 finding from 1 review
Dental caries · Children aged 2 to 8 years
The review reported a slightly higher odds ratio at maternal prenatal vitamin D ≤35 nmol/L than at ≤50 nmol/L, without a numeric value in the available sources.
1 finding from 1 review
Streptococcus mutans count · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
No difference in mean Streptococcus mutans presence was reported; GRADE was not reported.
1 finding from 1 review