Question · asked by 1 review

Cleft lip and/or palate (CL/P) vs No cleft lip and/or palate (non-CL/P): Lactobacillus spp. mean levels/counts

Population
Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
Intervention
Cleft lip and/or palate (CL/P)
Comparison
No cleft lip and/or palate (non-CL/P)
Outcome
Lactobacillus spp. mean levels/counts

No significant difference in Lactobacillus spp. presence was reported; GRADE was not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Cleft lip and palate vs No cleft lip and palate
Lactobacillus spp. mean levels/counts · Children and adolescents aged 0 to 18 years with nonsyndromic cleft lip and palate
No significant difference in Lactobacillus spp. presence was reported; GRADE was not reported.
Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and… (2024) All outcomes
MD 1.40 [1.33, 1.47]2 studies · 152 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and periodontal status in children and…
2024 All outcomes
Publications from 1 January 1985 to 30 June 2020 (search date not separately reported)24Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.