Question · asked by 1 review

Breastfeeding vs No breastfeeding: Early childhood caries (ECC)

Population
Preschool children (<6 years)
Intervention
Breastfeeding
Comparison
No breastfeeding
Outcome
Early childhood caries (ECC)

After excluding five studies, breastfeeding was associated with lower ECC risk in cohort studies (RR 0.82, 95% CI 0.71 to 0.95; I²=0%).

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Breastfeeding vs No breastfeeding
Dental caries (ECC) · Preschool children under 6 years of age · First dental examination before age 6 years, Clinical, field, or unclear dental examination settings, Cohort studies; sensitivity analysis excluding studies 37, 41, 45, 53, and 56
After excluding five studies, breastfeeding was associated with lower ECC risk in cohort studies (RR 0.82, 95% CI 0.71 to 0.95; I²=0%).
Association of Breastfeeding and Early Childhood Caries: A Systematic Review and Meta-Analysis. (2024) All outcomes
RR 0.82 [0.71, 0.95]5 studiesGRADE not reported
Breastfeeding (exclusive or partial, any duration) vs No breastfeeding
Dental caries (early childhood caries) · Preschool children (<6 years) · Preschool children in high- and middle-income countries; caries assessed in clinical or field/community settings, Case-control studies
In case-control studies, any breastfeeding versus no breastfeeding was not significantly associated with early childhood caries (OR 1.04, 95% CI 0.78-1.38; ungraded).
Association of Breastfeeding and Early Childhood Caries: A Systematic Review and Meta-Analysis. (2024) All outcomes
OR 1.04 [0.78, 1.38]5 studies · 1022 participantsGRADE not reported
Breastfeeding (exclusive or partial, any duration) vs No breastfeeding
Dental caries (early childhood caries) · Preschool children (<6 years) · Preschool children in high- and middle-income countries; caries assessed in clinical or field/community settings, Cohort studies
In cohort studies, any breastfeeding versus no breastfeeding was not significantly associated with early childhood caries (RR 0.98, 95% CI 0.77-1.26; high heterogeneity; ungraded).
Association of Breastfeeding and Early Childhood Caries: A Systematic Review and Meta-Analysis. (2024) All outcomes
RR 0.98 [0.77, 1.26]10 studies · 8506 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Association of Breastfeeding and Early Childhood Caries: A Systematic Review and Meta-Analysis.
2024 All outcomes
13 May 2023 (databases searched from inception)61Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.