Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy) vs Adequate prenatal vitamin D (sufficient maternal 25(OH)D): Dental caries
- Population
- Children aged 2 to 8 years
- Intervention
- Prenatal vitamin D deficiency (low maternal 25(OH)D during pregnancy)
- Comparison
- Adequate prenatal vitamin D (sufficient maternal 25(OH)D)
- Outcome
- Dental caries
The review reported an OR of 1.32 when prenatal vitamin D was measured at 6 to 38 gestational weeks.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Prenatal vitamin D deficiency measured at 6 to 38 gestational weeks vs Normal or sufficient prenatal vitamin D level Dental caries · Children aged 2 to 8 years · Maternal gestational weeks 6 to 38, Mostly developed countries (Europe and America), Vitamin D measurement at 6 to 38 gestational weeks The review reported an OR of 1.32 when prenatal vitamin D was measured at 6 to 38 gestational weeks. Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) All outcomes | OR 1.32 | Not reported | GRADE not reported |
Prenatal vitamin D deficiency (PVDD) vs Normal or sufficient prenatal vitamin D level Dental caries · Children aged 2 to 8 years · Maternal pregnancy to child age 2 to 8 years, Mostly developed countries (Europe and America), Meta-regression adjusted for gestational age, child age, and maternal vitamin D level After adjustment for the stated covariates, the review reported an estimate of 1.28 for dental caries risk. Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic… (2024) All outcomes | OR 1.28 [1.23, 1.33] | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Association between prenatal vitamin D deficiency with dental caries in infants and children: a systematic review and meta-analysis. 2024 All outcomes | 5 October 2023 (search range 2000 to October 2023) | 16 | Not applicable |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Impact of a Prenatal Vitamin D Supplementation Program on Vitamin D Deficiency, Rickets and Early Childhood Caries in an Alaska Native… · 2022 · included by 1 of these review
- Associations Between Prenatal, Perinatal, and Early Childhood Vitamin D Status and Risk of Dental Caries at 6 Years. · 2021 · included by 1 of these review
- Vitamin D, pregnancy and caries in children in the INMA-Asturias birth cohort. · 2021 · included by 1 of these review
- Association of Maternal Vitamin D Deficiency with Early Childhood Caries. · 2019 · included by 1 of these review
- Higher vitamin D intake during pregnancy is associated with reduced risk of dental caries in young Japanese children · 2015 · included by 1 of these review
- Prenatal Vitamin D and Dental Caries in Infants · 2014 · included by 1 of these review
- Interobserver agreement of the TASC II classification for supra- and infrainguinal lesions. · 2010 · included by 1 of these review
- Tecovirimat, a p37 envelope protein inhibitor for the treatment of smallpox infection. · 2010 · included by 1 of these review
- Direct measurement of the accuracy of CO(2)laser alignment on target. · 1978 · included by 1 of these review
- Beckett 2022 · included by 1 of these review
- Christensen 2016 · included by 1 of these review
- Olczak-Kowalczyk 2021 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.