Findings

What do systematic reviews say?

61 questions · 65 findings · 28 reviews

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No studies found 40 · 61.5%GRADE not reported 4 · 6.2%Very low 5 · 7.7%Low 7 · 10.8%Moderate 6 · 9.2%High 3 · 4.6%

Antibiotics vs other antibiotics

Quality of life ‐ not reported · farmworkers

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for leptospirosis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs another topical antibiotic or placebo

Quality of life at 1 month · children and adults with corneal abrasion

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for corneal abrasion 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs boric acid

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs povidone‐iodine

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

Quality of life: CFQ‐R respiratory domain: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen

1 finding from 1 review

Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Topical antibiotics with steroids vs placebo/no treatment

Health‐related quality of life · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics at time of replacement vs no antibiotics at time of replacement

Disease‐specific quality of life ‐ not reported · adults with replacing long‐term indwelling urinary catheters

The review found no eligible studies for this question.

1 finding from 1 review

Policies for replacing long‐term indwelling urinary catheters in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Combined HBO and perioperative antibiotics prior to dental implant therapy vs antibiotics alone

Adverse effects (including quality of life) · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)

1 finding from 1 review

Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy 2019 · Cochrane All outcomes
1 year
This comparison was only made in 1 study which reported no serious adverse events associated with HBO therapy. Quality of life measures (oral status, functioning, satisfaction) showed emotional functioning and pain…
1 study · 26 participants
Very low

Summary of findings: anti‐pseudomonal antibiotics vs placebo

Quality of life: lost school or working days · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 245 participants
Low

Antibiotics vs placebo or no intervention

Quality of life ‐ not reported · farmworkers, soldiers, and people in endemic areas

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic prophylaxis for leptospirosis 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Single vs combination IV antibiotics

Quality of life · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: inhaled TOBI® (IV preparation) vs tobramycin

Quality of life · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: tobramycin for inhalation powder vs tobramycin

Quality of life · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

The review found no eligible studies for this question.

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral + inhaled dual therapy vs oral monotherapy

Quality of life · bronchiectasis

1 finding from 1 review

Dual antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Polymyxins vs aminoglycosides

Quality of life · adults with bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Head‐to‐head trials of antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fluoroquinolones vs amoxicillin

Quality of life · adults aged 18 years and above with diagnosis of non‐cystic fibrosis bronchiectasis

The review found no eligible studies for this question.

1 finding from 1 review

Head‐to‐head trials of antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Quality of life · cancer patients receiving myelotoxic chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antibiotics or G(M)‐CSF for the prevention of infections and improvement of survival in cancer patients… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Health‐related quality of life

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube)… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Macrolides vs placebo

Quality of life: change · adults with bronchiectasis

1 finding from 1 review

Macrolide antibiotics for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 305 participants
Low