Cochrane · systematic review · CD011684
Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube) insertion
Venekamp, RP, Javed, F, van Dongen, TMA, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
ENTAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
8
No studies
1
Included studies
NR
No studies 1 · 11.1%Ungraded 0 · 0%Very low 1 · 11.1%Low 4 · 44.4%Moderate 3 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antibiotic eardrops (with or without a corticosteroid) versus oral antibiotics in children with grommets (ventilation tubes) who develop ear discharge beyond the immediate postoperative period
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Resolution of ear discharge at short‐term Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | RR 2.58 [1.27, 5.22] | 1 study · 42 participants | Moderate Downgraded: imprecision |
Adverse events Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | RR 0.37 [0.12, 1.09] | 3 studies · 705 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Serious complications Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | no estimate extracted | 1 study · 153 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Resolution of ear discharge at intermediate‐term Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | RR 1.7 [1.38, 2.08] | 1 study · 153 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Duration of ear discharge Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | no estimate extracted | 2 studies · 232 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency |
Tube blockage Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | RR 1.2 [0.33, 4.45] | 2 studies · 121 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Health‐related quality of life Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | no estimate extracted | NR | No studies |
Generic ‐ CHQ Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | no estimate extracted | 1 study · 153 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Disease‐specific ‐ OM‐6 (range 6 to 42) Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics | no estimate extracted | 1 study · 153 participants | Low Downgraded: risk of bias, imprecision, inconsistency |