Cochrane · systematic review · CD014617
Antibiotic prophylaxis for corneal abrasion
Algarni, AM, Guyatt, GH, Turner, A, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
4
Included studies
NR
No studies 4 · 57.1%Ungraded 0 · 0%Very low 2 · 28.6%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Topical antibiotics compared with another topical antibiotic or placebo for corneal abrasion
Population: children and adults with corneal abrasion
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Risk of any ocular infection within 1 month following corneal abrasion Topical antibiotics vs another topical antibiotic or placebo | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, indirectness |
Time to clinical cure, defined as complete healing (re‐epithelialization) of the epithelium Topical antibiotics vs another topical antibiotic or placebo | no estimate extracted | NR | Very low Downgraded: risk of bias, imprecision, indirectness |
Change in pain intensity from baseline to 1 month Topical antibiotics vs another topical antibiotic or placebo | no estimate extracted | NR | No studies |
Recurrent corneal erosion within 1 year Topical antibiotics vs another topical antibiotic or placebo | no estimate extracted | NR | No studies |
Change in visual acuity from baseline to 1 year, or loss of 1 or more lines of best‐corrected visual acuity at 1 month Topical antibiotics vs another topical antibiotic or placebo | no estimate extracted | NR | No studies |
Quality of life at 1 month Topical antibiotics vs another topical antibiotic or placebo | no estimate extracted | NR | No studies |
Adverse effects Topical antibiotics vs another topical antibiotic or placebo | no estimate extracted | NR | Low Downgraded: risk of bias, imprecision |