Findings

What do systematic reviews say?

45 questions · 45 findings · 24 reviews

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No studies found 7 · 15.6%GRADE not reported 2 · 4.4%Very low 26 · 57.8%Low 7 · 15.6%Moderate 3 · 6.7%High 0 · 0%

Low‐pressure vs standard pressure pneumoperitoneum

All‐cause mortality · patients with laparoscopic cholecystectomy.

1 finding from 1 review

Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 434 participants
Very low

Infiltration injection local anaesthetic vs no local anaesthetic wound infiltration

All‐cause mortality · patients with people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 539 participants
Very low

Local anaesthetic wound infiltration before incision vs end of surgery

All‐cause mortality · patients with people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Intervention not reported

Mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 137 participants
Very low

Fewer‐than‐four ports vs four ports

All‐cause mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Fewer‐than‐four ports versus four ports for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 634 participants
Very low

Various interventions vs control

All‐cause mortality · people undergoing laparoscopic cholecystectomy.

1 finding from 1 review

Pharmacological interventions for prevention or treatment of postoperative pain in people undergoing laparoscopic… 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 123 participants
Very low

Intervention not reported

Mortality · people undergoing laparoscopic cholecystectomy

1 finding from 1 review

Methods of intraperitoneal local anaesthetic instillation for laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 206 participants
Very low

Supplementary box model training vs standard training

All‐cause mortality · surgical trainees with limited prior laparoscopic experience

1 finding from 1 review

Laparoscopic surgical box model training for surgical trainees with limited prior laparoscopic experience 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 168 participants
Very low

Early vs delayed laparoscopic cholecystectomy

All‐cause mortality · people with acute cholecystitis.

1 finding from 1 review

Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis 2013 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 438 participants
Very low

Routine abdominal drain vs No drain

All‐cause mortality · patients with laparoscopic cholecystectomy.

It is very uncertain whether routine abdominal drain changes mortality compared with 'no drain' (very low certainty).

1 finding from 1 review

Routine abdominal drainage versus no abdominal drainage for uncomplicated laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
RR 0.41 [0.04, 4.37]
10 studies · 1681 participants
Very low

Early vs delayed laparoscopic cholecystectomy

All‐cause mortality · people with biliary colic

It is very uncertain whether early changes mortality compared with delayed laparoscopic cholecystectomy (very low certainty).

1 finding from 1 review

Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic 2013 · Cochrane Headline outcomes only
RR 0.38 [0.02, 9.03]
1 study · 75 participants
Very low

Early vs delayed laparoscopic appendicectomy

All‐cause mortality · paediatric participants with appendiceal abscess

1 finding from 1 review

Early versus delayed appendicectomy for appendiceal phlegmon or abscess 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Low tidal volume vs high tidal volume

All‐cause mortality · adults (aged > 16 years) without acute lung injury needing mechanical positive pressure ventilation during their surgery and undergoing…

Low tidal volume showed no clear difference in mortality compared with high tidal volume (low certainty).

1 finding from 1 review

Intraoperative use of low volume ventilation to decrease postoperative mortality, mechanical ventilation, lengths of… 2018 · Cochrane Headline outcomes only
RR 0.8 [0.42, 1.53]
12 studies · 1207 participants
Low

Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open)

All‐cause mortality · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 107 participants
Moderate

Laparaoscopic gastric imbrication vs laparoscopic sleeve gastrectomy

All‐cause mortality · participants with obesity

1 finding from 1 review

Surgery for weight loss in adults 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Day‐surgery vs overnight stay surgery

Short term mortality · patients with laparoscopic cholecystectomy.

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB

All‐cause mortality short‐term · adults undergoing intra‐ and transperitoneal laparoscopic procedures

It is very uncertain whether summary of findings table ‐ Deep neuromuscular blockade (NMB) changes all‐cause mortality short‐term compared with moderate NMB (very low certainty).

1 finding from 1 review

Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure 2024 · Cochrane Headline outcomes only
Peto OR 7.22 [0.45, 115.43]
12 studies · 1390 participants
Very low

Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB

All‐cause mortality ‐ not reported · adults undergoing intra‐ and transperitoneal laparoscopic procedures

The review found no eligible studies for this question.

1 finding from 1 review

Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Open‐entry vs closed entry technique

All‐cause mortality · patients undergoing laparoscopy

1 finding from 1 review

Laparoscopic entry techniques 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 715 participants
GRADE not reported

Direct vision entry vs Veress needle entry

All‐cause mortality · patients undergoing laparoscopy

The review found no eligible studies for this question.

1 finding from 1 review

Laparoscopic entry techniques 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found