Cochrane · systematic review · CD003641
Surgery for weight loss in adults
Colquitt, JL, Pickett, K, Loveman, E, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Metabolic and Endocrine DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
42
current version
GRADE rated
30
No studies
12
Included studies
NR
No studies 12 · 28.6%Ungraded 0 · 0%Very low 19 · 45.2%Low 2 · 4.8%Moderate 9 · 21.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Surgery compared with no surgery for obesity
Population: participants with obesity
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BMI at study end [kg/m²] Surgery vs no surgery | no estimate extracted | 5 studies · 582 participants | Moderate Downgraded: risk of bias |
Health‐related quality of life Short Form Health Survey (SF‐36) Surgery vs no surgery | no estimate extracted | 2 studies · 140 participants | Moderate Downgraded: risk of bias |
Comobidities: diabetes Different definitions used Surgery vs no surgery | no estimate extracted | 5 studies · 442 participants | Moderate Downgraded: risk of bias |
Mortality Surgery vs no surgery | no estimate extracted | 5 studies · 478 participants | Moderate |
Serious adverse events (SAEs) [%] Surgery vs no surgery | no estimate extracted | 4 studies · 438 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Reoperations [%] Surgery vs no surgery | no estimate extracted | 5 studies · 470 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Laparoscopic gastric bypass compared with laparoscopic adjustable gastric banding for obesity
Population: participants with obesity
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BMI at study end [kg/m²] Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding | no estimate extracted | 3 studies · 265 participants | Moderate Downgraded: risk of bias |
Health‐related quality of life Short Form Health Survey (SF‐36) Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding | no estimate extracted | 1 study · 250 participants | Very low Downgraded: risk of bias |
Comorbidities:diabetes Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding | no estimate extracted | 1 study · 51 participants | Very low Downgraded: risk of bias |
Mortality Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding | no estimate extracted | 2 studies · 301 participants | Moderate |
Serious adverse events (SAEs) Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding | no estimate extracted | NR | No studies |
Reoperations [%] Laparoscopic gastric bypass vs laparoscopic adjustable gastric banding | no estimate extracted | 2 studies · 240 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Laparoscopic Roux‐en‐Y gastric bypass compared with laparoscopic sleeve gastrectomy for obesity
Population: participants with obesity
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BMI at study end [kg/m²] Laparoscopic Roux‐en‐Y gastric bypass vs laparoscopic sleeve gastrectomy | no estimate extracted | 6 studies · 353 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Health‐related quality of life Laparoscopic Roux‐en‐Y gastric bypass vs laparoscopic sleeve gastrectomy | no estimate extracted | 1 study · 217 participants | Very low Downgraded: risk of bias |
Comorbidities: diabetes [different definitions used] Laparoscopic Roux‐en‐Y gastric bypass vs laparoscopic sleeve gastrectomy | no estimate extracted | 6 studies · 353 participants | Low Downgraded: risk of bias, imprecision |
Mortality Laparoscopic Roux‐en‐Y gastric bypass vs laparoscopic sleeve gastrectomy | no estimate extracted | 6 studies · 600 participants | Moderate |
Serious adverse events (SAEs) [%] Laparoscopic Roux‐en‐Y gastric bypass vs laparoscopic sleeve gastrectomy | no estimate extracted | 1 study · 217 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Reoperations [%] Laparoscopic Roux‐en‐Y gastric bypass vs laparoscopic sleeve gastrectomy | no estimate extracted | 2 studies · 277 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Gastric bypass versus biliopancreatic diversion with duodenal switch (laparoscopic or open) for obesity
Population: participants with obesity
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BMI reduction at study end [kg/m²] Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open) | no estimate extracted | 2 studies · 107 participants | Moderate |
Health‐related quality of life Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open) | no estimate extracted | 1 study · 60 participants | Very low Downgraded: risk of bias, indirectness |
Comorbidities: diabetes Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open) | no estimate extracted | 1 study · 60 participants | Very low Downgraded: risk of bias, indirectness |
Mortality Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open) | no estimate extracted | 2 studies · 107 participants | Moderate |
Serious adverse events (SAEs) Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open) | no estimate extracted | NR | No studies |
Reoperations [%] Gastric bypass vs biliopancreatic diversion with duodenal switch (laparoscopic or open) | no estimate extracted | 2 studies · 107 participants | Very low Downgraded: risk of bias, inconsistency |
Laparoscopic gastric bypass compared with laparoscopic duodenojejunal bypass with sleeve gastrectomy for obesity
Population: participants with obesity
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BMI at study end [kg/m²] Laparoscopic gastric bypass vs laparoscopic duodenojejunal bypass with sleeve gastrectomy | no estimate extracted | 1 study · 57 participants | Very low Downgraded: risk of bias |
Health‐related quality of life Laparoscopic gastric bypass vs laparoscopic duodenojejunal bypass with sleeve gastrectomy | no estimate extracted | NR | No studies |
Comorbiditites: diabetes [Proportions with complete remission and partial remission] Laparoscopic gastric bypass vs laparoscopic duodenojejunal bypass with sleeve gastrectomy | no estimate extracted | 1 study · 57 participants | Very low Downgraded: risk of bias |
Mortality Laparoscopic gastric bypass vs laparoscopic duodenojejunal bypass with sleeve gastrectomy | no estimate extracted | 1 study · 57 participants | Very low Downgraded: risk of bias |
Serious adverse events (SAEs) Laparoscopic gastric bypass vs laparoscopic duodenojejunal bypass with sleeve gastrectomy | no estimate extracted | NR | No studies |
Reoperations [%] Laparoscopic gastric bypass vs laparoscopic duodenojejunal bypass with sleeve gastrectomy | no estimate extracted | NR | No studies |
Laparoscopic adjustable gastric banding compared with laparoscopic isolated sleeve gastrectomy for obesity
Population: participants with obesity
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Reduction in BMI [kg/m²] Laparoscopic adjustable gastric banding vs laparoscopic isolated sleeve gastrectomy | no estimate extracted | 1 study · 80 participants | Very low Downgraded: risk of bias |
Health‐related quality of life Laparoscopic adjustable gastric banding vs laparoscopic isolated sleeve gastrectomy | no estimate extracted | NR | No studies |
Comorbidities: diabetes Laparoscopic adjustable gastric banding vs laparoscopic isolated sleeve gastrectomy | no estimate extracted | NR | No studies |
Mortality Laparoscopic adjustable gastric banding vs laparoscopic isolated sleeve gastrectomy | no estimate extracted | NR | No studies |
Serious adverse events (SAEs) Laparoscopic adjustable gastric banding vs laparoscopic isolated sleeve gastrectomy | no estimate extracted | NR | No studies |
Reoperations [%] Laparoscopic adjustable gastric banding vs laparoscopic isolated sleeve gastrectomy | no estimate extracted | 1 study · 80 participants | Very low Downgraded: risk of bias |
Laparaoscopic gastric imbrication compared with laparoscopic sleeve gastrectomy for obesity
Population: participants with obesity
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
BMI at study end [kg/m²] Laparaoscopic gastric imbrication vs laparoscopic sleeve gastrectomy | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |
Health‐related quality of life Laparaoscopic gastric imbrication vs laparoscopic sleeve gastrectomy | no estimate extracted | NR | No studies |
Comorbidities Laparaoscopic gastric imbrication vs laparoscopic sleeve gastrectomy | no estimate extracted | NR | No studies |
Mortality Laparaoscopic gastric imbrication vs laparoscopic sleeve gastrectomy | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |
Serious adverse events (SAEs) Laparaoscopic gastric imbrication vs laparoscopic sleeve gastrectomy | no estimate extracted | NR | No studies |
Reoperations [%] Laparaoscopic gastric imbrication vs laparoscopic sleeve gastrectomy | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |