Cochrane · systematic review · CD013197
Deep neuromuscular blockade in adults undergoing an abdominal laparoscopic procedure
Bijkerk, V, Jacobs, LMC, Albers, KI, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
6
No studies
4
Included studies
NR
No studies 4 · 40%Ungraded 0 · 0%Very low 5 · 50%Low 0 · 0%Moderate 1 · 10%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Deep neuromuscular blockade (NMB) compared to moderate NMB in adults undergoing intra‐ and transperitoneal laparoscopic procedures
Population: adults undergoing intra‐ and transperitoneal laparoscopic procedures
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality short‐term Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB | Peto OR 7.22 [0.45, 115.43] | 12 studies · 1390 participants | Very low Downgraded: risk of bias, imprecision |
Health‐related quality of life Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB | no estimate extracted | 5 studies · 440 participants | Moderate Downgraded: risk of bias |
Serious adverse events (SAEs) start of surgery until 8 hours after surgery Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB | Peto OR 0.95 [0.59, 1.52] | 21 studies · 2231 participants | Very low Downgraded: risk of bias, imprecision |
Short‐term serious adverse events (SAEs) Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs moderate NMB | Peto OR 0.9 [0.56, 1.42] | 16 studies · 1764 participants | Very low Downgraded: risk of bias, imprecision |
Summary of findings table ‐ Deep neuromuscular blockade (NMB) compared to shallow NMB in adults undergoing intra‐ and transperitoneal laparoscopic procedures
Population: adults undergoing intra‐ and transperitoneal laparoscopic procedures
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality ‐ not reported Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB | no estimate extracted | NR | No studies |
Health‐related quality of life ‐ not reported Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB | no estimate extracted | NR | No studies |
Short‐term serious adverse events (SAEs) Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs shallow NMB | RR 1.66 [0.5, 5.57] | 2 studies · 158 participants | Very low Downgraded: risk of bias, imprecision |
Summary of findings table ‐ Deep neuromuscular blockade (NMB) compared to no NMB in adults undergoing intra‐ and transperitoneal laparoscopic procedures
Population: adults undergoing intra‐ and transperitoneal laparoscopic procedures
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality start of surgery ‐ not reported Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs no NMB | no estimate extracted | NR | No studies |
Health‐related quality of life ‐ not reported Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs no NMB | no estimate extracted | NR | No studies |
Serious adverse events (SAEs) start of surgery until 8 hours after surgery Summary of findings table ‐ Deep neuromuscular blockade (NMB) vs no NMB | no estimate extracted | 1 study · 25 participants | Very low Downgraded: risk of bias, imprecision |