Cochrane · systematic review · CD007049
Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy
Loizides, S, Gurusamy, KS, Nagendran, M, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
18
current version
GRADE rated
18
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 17 · 94.4%Low 1 · 5.6%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Local anaesthetic wound infiltration compared to no local anaesthetic wound infiltration for people undergoing laparoscopic cholecystectomy
Population: patients with people undergoing laparoscopic cholecystectomy.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Local anaesthetic wound infiltration vs no local anaesthetic wound infiltration | no estimate extracted | 7 studies · 539 participants | Very low Downgraded: risk of bias |
Serious adverse events Local anaesthetic wound infiltration vs no local anaesthetic wound infiltration | RR 2 [0.19, 21.59] | 7 studies · 539 participants | Very low Downgraded: risk of bias |
Proportion discharged as day surgery Local anaesthetic wound infiltration vs no local anaesthetic wound infiltration | RR 1.55 [1.05, 2.28] | 1 study · 97 participants | Very low Downgraded: risk of bias |
Length of hospital stay Local anaesthetic wound infiltration vs no local anaesthetic wound infiltration | no estimate extracted | 4 studies · 327 participants | Very low Downgraded: risk of bias, inconsistency |
Pain 4 to 8 hours Local anaesthetic wound infiltration vs no local anaesthetic wound infiltration | no estimate extracted | 13 studies · 806 participants | Very low Downgraded: risk of bias, inconsistency |
Pain 9 to 24 hours Local anaesthetic wound infiltration vs no local anaesthetic wound infiltration | no estimate extracted | 12 studies · 756 participants | Low Downgraded: risk of bias |
Return to normal activity Local anaesthetic wound infiltration vs no local anaesthetic wound infiltration | no estimate extracted | 2 studies · 195 participants | Very low Downgraded: risk of bias |
Wound infiltration with different local anaesthetic agents for people undergoing laparoscopic cholecystectomy
Population: people undergoing laparoscopic cholecystectomy.
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality | no estimate extracted | 1 study · 137 participants | Very low Downgraded: risk of bias |
Serious adverse events | no estimate extracted | 1 study · 137 participants | Very low Downgraded: risk of bias |
Length of hospital stay | no estimate extracted | 1 study · 137 participants | Very low Downgraded: risk of bias |
Return to normal activity | no estimate extracted | 1 study · 137 participants | Very low Downgraded: risk of bias |
Pain 4 to 8 hours | no estimate extracted | 1 study · 39 participants | Very low Downgraded: risk of bias |
Pain 9 to 24 hours | no estimate extracted | 1 study · 39 participants | Very low Downgraded: risk of bias |
Local anaesthetic wound infiltration before incision compared to end of surgery for people undergoing laparoscopic cholecystectomy
Population: patients with people undergoing laparoscopic cholecystectomy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Mortality Local anaesthetic wound infiltration before incision vs end of surgery | no estimate extracted | 1 study · 43 participants | Very low Downgraded: risk of bias |
Serious adverse events Local anaesthetic wound infiltration before incision vs end of surgery | no estimate extracted | 1 study · 43 participants | Very low Downgraded: risk of bias |
Pain 4 to 8 hours Local anaesthetic wound infiltration before incision vs end of surgery | no estimate extracted | 2 studies · 76 participants | Very low Downgraded: risk of bias |
Pain 9 to 24 hours Local anaesthetic wound infiltration before incision vs end of surgery | no estimate extracted | 1 study · 40 participants | Very low Downgraded: risk of bias |
Return to normal activity Local anaesthetic wound infiltration before incision vs end of surgery | no estimate extracted | 1 study · 30 participants | Very low Downgraded: risk of bias |