Cochrane · systematic review · CD008261

Pharmacological interventions for prevention or treatment of postoperative pain in people undergoing laparoscopic cholecystectomy

Gurusamy, KS, Vaughan, J, Toon, CD, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
1
Included studies
NR
No studies 1 · 14.3%Ungraded 0 · 0%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Various interventions compared with control for people undergoing laparoscopic cholecystectomy

Population: people undergoing laparoscopic cholecystectomy
7 questions
OutcomeEffectEvidenceStatus / GRADE
Morbidity
Various interventions vs control
RR 0.75 [0.37, 1.53]5 studies · 543 participantsVery low
Downgraded: risk of bias
Proportion discharged as day‐surgery
Various interventions vs control
RR 1 [0.74, 1.34]1 study · 116 participantsVery low
Downgraded: risk of bias
Length of hospital stay
Various interventions vs control
no estimate extracted1 study · 119 participantsVery low
Downgraded: risk of bias
Pain (4 to 8 hours)
Various interventions vs control
no estimate extracted11 studies · 999 participantsVery low
Downgraded: risk of bias, inconsistency
Pain (9 to 24 hours)
Various interventions vs control
no estimate extracted9 studies · 707 participantsVery low
Downgraded: risk of bias, inconsistency
Mortality
Various interventions vs control
no estimate extracted1 study · 123 participantsVery low
Downgraded: risk of bias
Opioids versus NSAIDs
Various interventions vs control
no estimate extractedNRNo studies