Cochrane · systematic review · CD005440

Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis

Gurusamy, KS, Davidson, C, Gluud, C, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 71.4%Low 0 · 0%Moderate 2 · 28.6%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Early versus delayed laparoscopic cholecystectomy for acute cholecystitis

Population: people with acute cholecystitis.
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality
Early vs delayed laparoscopic cholecystectomy
no estimate extracted5 studies · 438 participantsVery low
Downgraded: risk of bias
Bile duct injury
Early vs delayed laparoscopic cholecystectomy
Peto OR 0.49 [0.05, 4.72]5 studies · 438 participantsVery low
Downgraded: risk of bias, imprecision
Other serious complications
Early vs delayed laparoscopic cholecystectomy
RR 1.29 [0.61, 2.72]5 studies · 438 participantsVery low
Downgraded: risk of bias, imprecision
Conversion to open cholecystectomy
Early vs delayed laparoscopic cholecystectomy
RR 0.89 [0.63, 1.25]6 studies · 488 participantsVery low
Downgraded: risk of bias, imprecision
Hospital stay
Early vs delayed laparoscopic cholecystectomy
no estimate extracted4 studies · 373 participantsModerate
Downgraded: risk of bias
Operating time
Early vs delayed laparoscopic cholecystectomy
no estimate extracted6 studies · 488 participantsModerate
Downgraded: risk of bias
Return to work
Early vs delayed laparoscopic cholecystectomy
no estimate extracted1 study · 36 participantsVery low
Downgraded: risk of bias, inconsistency