Treatment failure ‐ need for systemic corticosteroids (ITT) · adults and children with chronic asthma
Increased showed no clear difference in treatment failure: need for systemic corticosteroids (ITT) compared with stable doses of inhaled corticosteroids (moderate certainty).
1 finding from 1 review
Treatment failure ‐ need for systemic corticosteroids (of those starting inhaler) · adults and children with chronic asthma
It is very uncertain whether increased changes treatment failure: need for systemic corticosteroids (of those… compared with stable doses of inhaled corticosteroids (very low certainty).
1 finding from 1 review
Rate of exacerbations requiring systemic corticosteroids · adults with asthma well controlled on LABA and ICS
Stopping LABA showed no clear difference in exacerbation: systemic corticosteroids 17 weeks compared with continuing use of LABA+ICS (moderate certainty).
1 finding from 1 review
Exacerbations (OCS) · adults with asthma not well controlled on ICS
LAMA add‐on leads to lower exacerbations requiring oral corticosteroids (OCS) compared with ICS alone (high certainty).
1 finding from 1 review
Intervention not reported
Exacerbations requiring oral corticosteroids 48 weeks · adults with asthma
The intervention showed no clear difference in exacerbations requiring oral corticosteroids 48 weeks (moderate certainty).
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · children with asthma
Anti‐leukotrienes & ICS may leads to lower participants with one or more exacerbations requiring oral… compared with same dose ICS (low certainty).
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · children with asthma
Anti‐leukotrienes & ICS may leads to lower participants with one or more exacerbations requiring oral… compared with higher dose ICS (low certainty).
1 finding from 1 review
Number of participants with exacerbations requiring systemic steroids · patients with chronic asthma
LABA + ICS leads to lower participants with one or more exacerbations requiring systemic… compared with LTRA + ICS (high certainty).
1 finding from 1 review
Any COPD exacerbation that requires short‐burst oral corticosteroids or antibiotics, or both · patients with chronic obstructive pulmonary disease
It is very uncertain whether once‐daily ICS/LABA combined inhalers changes any COPD exacerbation that requires short‐burst oral corticosteroids… compared with once‐daily LAMA (very low certainty).
1 finding from 1 review
Number of participants experiencing one or more episode requiring treatment with oral steroids · Children and adults with persistent asthma.
Intermittent 'as needed' ICS showed no clear difference in patients with 1 or more exacerbations requiring oral corticosteroids… compared with daily ICS (low certainty).
1 finding from 1 review
Intervention not reported
Patients with ≥ 1 exacerbation requiring oral corticosteroids Duration of trials: 8 to 13 weeks · adults and adolescents with persistent asthma
The intervention showed no clear difference in patients with ≥ 1 exacerbation requiring oral corticosteroids… (moderate certainty).
1 finding from 1 review
Intervention not reported
Patients with ≥ 1 exacerbations requiring oral corticosteroids Duration of trials: 6 to 16 weeks · adults and adolescents with persistent asthma
The intervention probably leads to lower patients with ≥ 1 exacerbations requiring oral corticosteroids… (moderate certainty).
1 finding from 1 review
Intervention not reported
Participants with ≥ 1 exacerbation requiring oral corticosteroids Duration of trials: 8 to 24 weeks · adults and adolescents with persistent asthma
The intervention showed no clear difference in participants with ≥ 1 exacerbation requiring oral corticosteroids… (low certainty).
1 finding from 1 review
Courses of oral corticosteroids · acute exacerbations of chronic obstructive pulmonary disease
1 finding from 1 review
Mean exacerbations requiring a course of oral corticosteroids · Preschool children (<6 years)
Intermittent ICS probably leads to lower exacerbations requiring oral corticosteroids compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Exacerbations requiring oral corticosteroids3 months · adults or children with asthma
The intervention showed no clear difference in exacerbations requiring oral corticosteroids3 months (low certainty).
1 finding from 1 review
Exacerbations requiring oral corticosteroids ‐ adults · School‐aged children and adults
Intermittent ICS showed no clear difference in exacerbations requiring oral corticosteroids ‐ adults compared with placebo (low certainty).
1 finding from 1 review
Intervention not reported
Exacerbations requiring oral corticosteroids 7.3‐month · people with asthma
The intervention showed no clear difference in exacerbations requiring oral corticosteroids 7.3‐month (low certainty).
1 finding from 1 review
Intervention not reported
Exacerbations requiring a course of oral corticosteroids · children and adolescents aged 18 years and under studies with asthma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean daily use of oral corticosteroids per person per day · people with asthma
1 finding from 1 review