Cochrane · systematic review · CD005603
Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults
Petsky, HL, Li, A, Chang, AB · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 40%Very low 0 · 0%Low 1 · 20%Moderate 2 · 40%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Tailored interventions based on sputum eosinophils compared to tailored interventions based on clinical symptoms for asthma in adults and children
Population: adults and children with asthma
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of participants who had one or more exacerbations over the study period Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms | OR 0.36 [0.21, 0.62] | 3 studies · 228 participants | Moderate Downgraded: inconsistency |
Hospitalisations Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms | OR 0.28 [0.09, 0.84] | 4 studies · 269 participants | Moderate Downgraded: imprecision |
Mean dose of inhaled corticosteroids per person per day (BUD equivalent mcg/day) Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms | no estimate extracted | 4 studies · 316 participants | Low Downgraded: imprecision, inconsistency |
Mean daily use of oral corticosteroids per person per day Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms | no estimate extracted | 1 study · 68 participants | Ungraded |
Yearly cost per person (USD) Tailored interventions based on sputum eosinophils vs tailored interventions based on clinical symptoms | no estimate extracted | 1 study · 68 participants | Ungraded |