Increased vs stable doses of inhaled corticosteroids: Treatment failure ‐ need for systemic corticosteroids (ITT)
Increased showed no clear difference in treatment failure: need for systemic corticosteroids (ITT) compared with stable doses of inhaled corticosteroids (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Increased vs stable doses of inhaled corticosteroids Treatment failure: need for systemic corticosteroids (ITT) · adults and children with chronic asthma Increased showed no clear difference in treatment failure: need for systemic corticosteroids (ITT) compared with stable doses of inhaled corticosteroids (moderate certainty). Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and… (2022) · Cochrane Headline outcomes only | OR 0.97 [0.76, 1.25] | 8 studies · 1774 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.