Tranexamic acid vs placebo
It is very uncertain whether tranexamic acid changes transfusion Number needing blood transfusion compared with placebo (very low certainty).
- RR 1.025 studies · 931 participantsVery low
It is very uncertain whether tranexamic acid changes transfusion Number needing blood transfusion compared with placebo (very low certainty).
Tranexamic acid may leads to lower transfusion Number of participants who required at least 1 blood… compared with cimetidine or lansoprazole (low certainty).
The review found no eligible studies for this question.
Tranexamic acid showed no clear difference in severity of re‐bleeding: proportion of patients requiring blood… compared with placebo plus usual care or usual care alone (low certainty).
Standard care plus IV tranexamic acid showed no clear difference in blood transfusion (any) compared with placebo or standard care alone (moderate certainty).
It is very uncertain whether topical tranexamic acid changes risk of requiring allogeneic blood transfusion (30 days post‐surgery) compared with placebo (very low certainty).
Intravenous tranexamic acid may leads to lower risk of requiring allogeneic blood transfusion (30 days post‐surgery) compared with placebo (low certainty).
It is very uncertain whether the intervention changes number of participants receiving blood transfusion: tranexamic acid… (very low certainty).
Systemic TXA probably leads to lower blood transfusion compared with no TXA (placebo or usual care) (moderate certainty).
Topical TXA probably leads to lower blood transfusion compared with no TXA (placebo or usual care) (moderate certainty).
The intervention showed no clear difference in rate of RBC transfusion (total number of participants who required… (low certainty).