Question · asked by 1 review

Tranexamic acid vs placebo: Blood transfusion

It is very uncertain whether tranexamic acid changes transfusion Number needing blood transfusion compared with placebo (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Tranexamic acid vs placebo
Transfusion Number needing blood transfusion · patients with upper gastrointestinal bleeding
It is very uncertain whether tranexamic acid changes transfusion Number needing blood transfusion compared with placebo (very low certainty).
Tranexamic acid for upper gastrointestinal bleeding (2014) · Cochrane Headline outcomes only
RR 1.025 studies · 931 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Tranexamic acid for upper gastrointestinal bleeding
2014 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.