Tranexamic acid vs placebo + standard care: Severity of re‐bleeding: proportion of patients requiring blood transfusion within 10 days
- Population
- adults with nasal haemorrhage (epistaxis)
- Intervention
- Tranexamic acid
- Comparison
- placebo + standard care
- Outcome
- Severity of re‐bleeding: proportion of patients requiring blood transfusion within 10 days
Tranexamic acid showed no clear difference in severity of re‐bleeding: proportion of patients requiring blood… compared with placebo plus usual care or usual care alone (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Tranexamic acid vs placebo plus usual care or usual care alone Severity of re‐bleeding: proportion of patients requiring blood transfusion within 10 days · adults with nasal haemorrhage (epistaxis) Tranexamic acid showed no clear difference in severity of re‐bleeding: proportion of patients requiring blood… compared with placebo plus usual care or usual care alone (low certainty). Tranexamic acid for patients with nasal haemorrhage (epistaxis) (2018) · Cochrane Headline outcomes only | RR 0.81 [0.27, 2.48] | 1 study · 89 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Tranexamic acid for patients with nasal haemorrhage (epistaxis) 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Tranexamic acid vs alternative haemostatic agents · adults with nasal haemorrhage (epistaxis) · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.