Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

40 questions · 42 findings · 17 reviews · Headline outcomes only

No studies found 22 · 52.4%GRADE not reported 5 · 11.9%Very low 12 · 28.6%Low 2 · 4.8%Moderate 1 · 2.4%High 0 · 0%

CBT vs TAU

AEs · chronic pain (excluding headache) in adults
3 findings from 2 reviews · compare the 2 reviews

Summary of findings table ‐ CBT without antipsychotics vs CBT plus antipsychotics

Risk for at least one adverse event per patient · schizophrenia

Summary of findings table ‐ CBT without antipsychotics may leads to lower adverse events ‐ Participants with at least one AE (separated time… compared with CBT plus antipsychotics (low certainty).

1 finding from 1 review

CBT plus standard care vs usual care

Adverse events experienced at short or long term ‐ general adverse events 24 weeks' · patients with schizophrenia

It is very uncertain whether COMPARISON 1: CBT+ STANDARD CARE changes adverse events: General: any adverse event compared with STANDARD CARE ALONE (very low certainty).

1 finding from 1 review