Cochrane · systematic review · CD007964

Cognitive behavioural therapy plus standard care versus standard care for people with schizophrenia

Jones, C, Hacker, D, Xia, J, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library

SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 71.4%Low 1 · 14.3%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

COMPARISON 1: CBT+ STANDARD CARE compared to STANDARD CARE ALONE for people with schizophrenia

Population: people with schizophrenia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Global state: 1a. Relapse ‐ long term
COMPARISON 1: CBT+ STANDARD CARE vs STANDARD CARE ALONE
RR 0.78 [0.61, 1]13 studies · 1538 participantsLow
Downgraded: inconsistency
Global state: 2. Clinically important change (no improvement) ‐ long term
COMPARISON 1: CBT+ STANDARD CARE vs STANDARD CARE ALONE
RR 0.57 [0.39, 0.84]2 studies · 82 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Mental state: General ‐ clinically important change (no improvement) ‐ long term
COMPARISON 1: CBT+ STANDARD CARE vs STANDARD CARE ALONE
RR 0.81 [0.65, 1.02]5 studies · 501 participantsVery low
Downgraded: inconsistency
Adverse events: General: any adverse event
COMPARISON 1: CBT+ STANDARD CARE vs STANDARD CARE ALONE
RR 0.44 [0.27, 0.72]2 studies · 146 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Functioning: Social (average endpoint score SOFAS, high = good) ‐ long term
COMPARISON 1: CBT+ STANDARD CARE vs STANDARD CARE ALONE
no estimate extracted2 studies · 295 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Quality of life: General (average endpoint score QLS, high = good) ‐ long term *
COMPARISON 1: CBT+ STANDARD CARE vs STANDARD CARE ALONE
no estimate extracted1 study · 71 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Satisfaction with treatment: 1. Leaving the study early ‐ long term
COMPARISON 1: CBT+ STANDARD CARE vs STANDARD CARE ALONE
RR 0.93 [0.77, 1.12]19 studies · 1945 participantsModerate
Downgraded: risk of bias, imprecision, inconsistency, indirectness