Cochrane · systematic review · CD007862

Active cycle of breathing technique for cystic fibrosis

Wilson, LM, Saldanha, IJ, Robinson, KA · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
35
current version
GRADE rated
9
No studies
16
Included studies
NR
No studies 16 · 45.7%Ungraded 10 · 28.6%Very low 8 · 22.9%Low 1 · 2.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Summary of findings: ACBT compared with CCPT for people with cystic fibrosis

Population: people with cystic fibrosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life
Summary of findings: ACBT vs CCPT
no estimate extractedNRNo studies
Personal preference
Summary of findings: ACBT vs CCPT
no estimate extractedNRNo studies
Adverse events
Summary of findings: ACBT vs CCPT
no estimate extractedNRNo studies
FEV1: % predicted (change from baseline)
Summary of findings: ACBT vs CCPT
no estimate extracted1 study · 1 participantsUngraded
FVC: % predicted (change from baseline)
Summary of findings: ACBT vs CCPT
no estimate extracted1 study · 1 participantsUngraded
Sputum weight (change from baseline)
Summary of findings: ACBT vs CCPT
no estimate extractedNRNo studies
Number of pulmonary exacerbations
Summary of findings: ACBT vs CCPT
RR 1.64 [0.62, 4.34]1 study · 63 participantsLow
Downgraded: risk of bias, imprecision

Summary of findings: ACBT compared with PEP mask therapy for people with cystic fibrosis

Population: people with cystic fibrosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life (change from baseline) SF‐36 score and CRQ score
Summary of findings: ACBT vs PEP mask therapy
no estimate extracted1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Personal preference
Summary of findings: ACBT vs PEP mask therapy
no estimate extractedNRNo studies
Adverse events
Summary of findings: ACBT vs PEP mask therapy
no estimate extractedNRNo studies
FEV1: % predicted (change from baseline)
Summary of findings: ACBT vs PEP mask therapy
no estimate extractedNRNo studies
FVC: % predicted (change from baseline)
Summary of findings: ACBT vs PEP mask therapy
no estimate extractedNRNo studies
Sputum weight (change from baseline)
Summary of findings: ACBT vs PEP mask therapy
no estimate extractedNRNo studies
Number of pulmonary exacerbations
Summary of findings: ACBT vs PEP mask therapy
no estimate extractedNRNo studies

Summary of findings: ACBT compared with OD for people with cystic fibrosis

Population: people with cystic fibrosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life (change from baseline) in SF‐36 score and CRQ score
Summary of findings: ACBT vs OD
no estimate extracted1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Personal preference
Summary of findings: ACBT vs OD
no estimate extracted6 participantsUngraded
Adverse events
Summary of findings: ACBT vs OD
no estimate extractedNRNo studies
FEV1: % predicted (change from baseline)
Summary of findings: ACBT vs OD
no estimate extracted6 participantsUngraded
FVC: % predicted (change from baseline)
Summary of findings: ACBT vs OD
no estimate extracted6 participantsUngraded
Sputum weight (change from baseline)
Summary of findings: ACBT vs OD
no estimate extracted6 participantsUngraded
Number of pulmonary exacerbations
Summary of findings: ACBT vs OD
no estimate extractedNRNo studies

Summary of findings: ACBT compared with other breathing techniques for people with cystic fibrosis

Population: people with cystic fibrosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life (change from baseline)
Summary of findings: ACBT vs other breathing techniques
no estimate extracted1 study · 30 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Personal preference
Summary of findings: ACBT vs other breathing techniques
no estimate extracted6 participantsUngraded
Adverse events
Summary of findings: ACBT vs other breathing techniques
no estimate extractedNRNo studies
FEV1: % predicted (change from baseline)
Summary of findings: ACBT vs other breathing techniques
no estimate extracted6 participantsUngraded
FVC: % predicted (change from baseline)
Summary of findings: ACBT vs other breathing techniques
no estimate extracted6 participantsUngraded
Sputum weight (change from baseline)
Summary of findings: ACBT vs other breathing techniques
no estimate extracted6 participantsUngraded
Number of pulmonary exacerbations
Summary of findings: ACBT vs other breathing techniques
no estimate extractedNRNo studies

Summary of findings: ACBT compared with exercise for people with cystic fibrosis

Population: people with cystic fibrosis
7 questions
OutcomeEffectEvidenceStatus / GRADE
Quality of life (change from baseline) CFQ‐R score
Summary of findings: ACBT vs exercise
no estimate extracted1 study · 19 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Personal preference
Summary of findings: ACBT vs exercise
no estimate extractedNRNo studies
Adverse events
Summary of findings: ACBT vs exercise
no estimate extracted1 study · 19 participantsVery low
Downgraded: risk of bias, imprecision
FEV1: % predicted (change from baseline)
Summary of findings: ACBT vs exercise
no estimate extracted1 study · 19 participantsVery low
Downgraded: risk of bias, imprecision
FVC: % predicted (change from baseline)
Summary of findings: ACBT vs exercise
no estimate extracted1 study · 19 participantsVery low
Downgraded: risk of bias, imprecision
Sputum weight (change from baseline)
Summary of findings: ACBT vs exercise
no estimate extractedNRNo studies
Number of pulmonary exacerbations
Summary of findings: ACBT vs exercise
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision