Cochrane · systematic review · CD012005
Interventions for fatigue in inflammatory bowel disease
Farrell, D, Artom, M, Czuber‐Dochan, W, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
38
current version
GRADE rated
29
No studies
9
Included studies
NR
No studies 9 · 23.7%Ungraded 0 · 0%Very low 19 · 50%Low 10 · 26.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Electroacupuncture compared to no treatment for participants with quiescent IBD
Population: participants with quiescent IBD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue Electroacupuncture vs no treatment | no estimate extracted | 1 study · 27 participants | Low Downgraded: imprecision |
Quality of life Electroacupuncture vs no treatment | no estimate extracted | 1 study · 27 participants | Low Downgraded: imprecision |
Adverse events Electroacupuncture vs no treatment | no estimate extracted | 1 study · 34 participants | Low Downgraded: imprecision |
Serious adverse events Electroacupuncture vs no treatment | no estimate extracted | 1 study · 34 participants | Low Downgraded: imprecision |
Withdrawal due to adverse events Electroacupuncture vs no treatment | no estimate extracted | 1 study · 34 participants | Low Downgraded: imprecision |
Electroacupuncture compared to sham electroacupuncture for participants with quiescent IBD
Population: participants with quiescent IBD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue Electroacupuncture vs sham electroacupuncture | no estimate extracted | 1 study · 30 participants | Low Downgraded: imprecision |
Quality of life Electroacupuncture vs sham electroacupuncture | no estimate extracted | 1 study · 30 participants | Low Downgraded: imprecision |
Adverse events Electroacupuncture vs sham electroacupuncture | OR 0.32 [0.01, 8.27] | 1 study · 36 participants | Low Downgraded: imprecision |
Serious adverse events Electroacupuncture vs sham electroacupuncture | no estimate extracted | 1 study · 36 participants | Low Downgraded: imprecision |
Withdrawal due to adverse events Electroacupuncture vs sham electroacupuncture | OR 0.32 [0.01, 8.27] | 1 study · 36 participants | Low Downgraded: imprecision |
CBT with therapist support compared to fatigue information leaflet only for participants with IBD
Population: participants with IBD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue CBT with therapist support vs fatigue information leaflet only | no estimate extracted | 1 study · 18 participants | Very low Downgraded: imprecision |
Fatigue CBT with therapist support vs fatigue information leaflet only | no estimate extracted | 1 study · 16 participants | Very low Downgraded: imprecision |
Quality of life CBT with therapist support vs fatigue information leaflet only | no estimate extracted | 1 study · 19 participants | Very low Downgraded: imprecision |
Adverse events CBT with therapist support vs fatigue information leaflet only | no estimate extracted | NR | No studies |
Serious adverse events CBT with therapist support vs fatigue information leaflet only | no estimate extracted | NR | No studies |
Withdrawal due to adverse events CBT with therapist support vs fatigue information leaflet only | no estimate extracted | NR | No studies |
Physical activity advice plus omega 3 compared to no physical activity advice plus omega 3 for participants with quiescent IBD
Population: participants with quiescent IBD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 25 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 25 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 25 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 25 participants | Very low Downgraded: imprecision |
Quality of life Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 25 participants | Very low Downgraded: imprecision |
Adverse events Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 25 participants | Very low Downgraded: imprecision |
Serious adverse events Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | NR | No studies |
Withdrawal due to adverse events Physical activity advice plus omega 3 vs no physical activity advice plus omega 3 | no estimate extracted | NR | No studies |
Physical activity advice plus placebo compared to no physical activity advice plus placebo for participants with quiescent IBD
Population: participants with quiescent IBD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue Physical activity advice plus placebo vs no physical activity advice plus placebo | no estimate extracted | 1 study · 27 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus placebo vs no physical activity advice plus placebo | no estimate extracted | 1 study · 27 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus placebo vs no physical activity advice plus placebo | no estimate extracted | 1 study · 27 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus placebo vs no physical activity advice plus placebo | no estimate extracted | 1 study · 27 participants | Very low Downgraded: imprecision |
Adverse events: Physical activity advice plus placebo vs no physical activity advice plus placebo | no estimate extracted | 1 study · 27 participants | Very low Downgraded: imprecision |
Serious adverse events ‐ not reported Physical activity advice plus placebo vs no physical activity advice plus placebo | no estimate extracted | NR | No studies |
Withdrawal due to adverse events ‐ not reported Physical activity advice plus placebo vs no physical activity advice plus placebo | no estimate extracted | NR | No studies |
Physical activity advice plus placebo compared to no physical activity advice plus omega 3 for participants with quiescent IBD
Population: participants with quiescent IBD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Fatigue Physical activity advice plus placebo vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 29 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus placebo vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 29 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus placebo vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 29 participants | Very low Downgraded: imprecision |
Fatigue Physical activity advice plus placebo vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 29 participants | Very low Downgraded: imprecision |
Adverse events: Physical activity advice plus placebo vs no physical activity advice plus omega 3 | no estimate extracted | 1 study · 29 participants | Very low Downgraded: imprecision |
Serious adverse events ‐ not reported Physical activity advice plus placebo vs no physical activity advice plus omega 3 | no estimate extracted | NR | No studies |
Withdrawal due to adverse events ‐ not reported Physical activity advice plus placebo vs no physical activity advice plus omega 3 | no estimate extracted | NR | No studies |