Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,949 questions · 1,994 findings · 636 reviews

No studies found 504 · 25.3%GRADE not reported 340 · 17.1%Very low 477 · 23.9%Low 390 · 19.6%Moderate 241 · 12.1%High 42 · 2.1%

Traditional suburethral sling operation vs a mid‐urethral sling or tape

Long‐term adverse effects Release of sling required · women with urinary incontinence

It is very uncertain whether traditional suburethral sling operation changes long‐term adverse effects Release of sling required compared with a mid‐urethral sling or tape (very low certainty).

1 finding from 1 review

Intervention not reported

Frequency of serious adverse effects 20 to 24 weeks · participants with moderate and severe acne

It is very uncertain whether the intervention changes frequency of serious adverse effects 20 to 24 weeks (very low certainty).

1 finding from 1 review

Muromonab‐CD3 (T cell) vs other antibody (stratified by comparator)

Neurological adverse effects · kidney transplant recipients: first rejection episode

Muromonab‐CD3 (T cell) may leads to higher treatment adverse events: neurological side effects compared with other antibody (stratified by comparator) (low certainty).

1 finding from 1 review

SULPIRIDE vs placebo

Severe adverse effects ‐ medium term ‐ not reported · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Topical capsaicin vs placebo

Withdrawals due to adverse events · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review

Oral gabapentin vs placebo

Withdrawals due to adverse events · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review

Oral glucosamine hydrochloride/chondroitin sulphate vs placebo

Withdrawals due to adverse events · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review

Oral clonazepam (benzodiazepine) vs placebo

Withdrawals due to adverse events · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review

Antihistamines vs scopolamine

Adverse effects: 1. Sedation · patients with motion sickness

It is very uncertain whether antihistamines changes adverse effects: sedation Assessed by: self‐reported compared with scopolamine (very low certainty).

1 finding from 1 review