Cochrane · systematic review · CD007811
Sulpiride versus placebo for schizophrenia
Wang, J, Sampson, S · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
2
No studies
5
Included studies
NR
No studies 5 · 71.4%Ungraded 0 · 0%Very low 2 · 28.6%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
SULPIRIDE compared to PLACEBO for schizophrenia
Population: people with schizophrenia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global state: clinically significant response in global state ‐ by long term ‐ not measured SULPIRIDE vs PLACEBO | no estimate extracted | NR | No studies |
Mental state: average score for positive symptoms (skewed) ‐ by short term Manchester Scale, positive subset endpoint SULPIRIDE vs PLACEBO | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision |
Mental state: average score for negative symptoms ‐ by short term Manchester Scale, negative subset endpoint. Scale from: 0 to 20. SULPIRIDE vs PLACEBO | no estimate extracted | 1 study · 18 participants | Very low Downgraded: risk of bias, imprecision |
Mental state: average score for depressive and anxious symptoms ‐ by medium term ‐ not measured SULPIRIDE vs PLACEBO | no estimate extracted | NR | No studies |
Quality of life: average score ‐ by long term ‐ not measured SULPIRIDE vs PLACEBO | no estimate extracted | NR | No studies |
Severe adverse effects ‐ medium term ‐ not reported SULPIRIDE vs PLACEBO | no estimate extracted | NR | No studies |
Safety assessments ‐ medium term ‐ not measured SULPIRIDE vs PLACEBO | no estimate extracted | NR | No studies |