Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,949 questions · 1,994 findings · 636 reviews

No studies found 504 · 25.3%GRADE not reported 340 · 17.1%Very low 477 · 23.9%Low 390 · 19.6%Moderate 241 · 12.1%High 42 · 2.1%

Summary of findings table ‐ Collagen vs standard diet or placebo

Adverse effects/events: at least 1 adverse effect ‐ as defined by individual studies. · adults with pressure ulcers

It is very uncertain whether summary of findings table ‐ Collagen changes side effects: at least one adverse event compared with standard diet or placebo (very low certainty).

1 finding from 1 review

Sulthiame vs levetiracetam

Adverse effects (central nervous system) · participants with epilepsy (BECTS)

Sulthiame showed no clear difference in adverse effects (central nervous system) compared with levetiracetam (low certainty).

1 finding from 1 review

FLUPHENAZINE DECANOATE vs ORAL NEUROLEPTICS

Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE DECANOATE changes extrapyramidal adverse effects ‐ general compared with ORAL NEUROLEPTICS (very low certainty).

1 finding from 1 review

FLUPHENAZINE DECANAOTE vs FLUPHENAZINE ENANTHATE

Adverse effects/events ‐ extrapyramidal symptoms ‐ medium term Number of instances of extrapyramidal symptoms · patients with schizophrenia

It is very uncertain whether FLUPHENAZINE DECANAOTE changes extrapyramidal adverse effects ‐ general compared with FLUPHENAZINE ENANTHATE (very low certainty).

1 finding from 1 review