Cochrane · systematic review · CD009692
Human albumin infusion for treating oedema in people with nephrotic syndrome
Ho, JJ, Adnan, AS, Kueh, YC, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 16.7%Ungraded 1 · 16.7%Very low 3 · 50%Low 0 · 0%Moderate 0 · 0%High 1 · 16.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Human albumin infusion plus furosemide compared to glucose for treating people with nephrotic syndrome
Population: patients of all ages with oedema due to nephrotic syndrome
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Weight loss rate up to day 10 after treatment Human albumin infusion plus furosemide vs glucose | no estimate extracted | 1 study · 26 participants | Very low Downgraded: risk of bias |
Others clinical improvement parameters: Serum sodium Human albumin infusion plus furosemide vs glucose | no estimate extracted | 1 study · 26 participants | Very low Downgraded: risk of bias |
Death Human albumin infusion plus furosemide vs glucose | no estimate extracted | 12 participants | Ungraded |
Kidney function Human albumin infusion plus furosemide vs glucose | no estimate extracted | 2 participants | High |
Quality of life Human albumin infusion plus furosemide vs glucose | no estimate extracted | NR | No studies |
Adverse effects: Systolic blood pressure Human albumin infusion plus furosemide vs glucose | no estimate extracted | 1 study · 26 participants | Very low Downgraded: risk of bias |