Cochrane · systematic review · CD011505
Oral galactagogues (natural therapies or drugs) for increasing breast milk production in mothers of non‐hospitalised term infants
Foong, SC, Tan, ML, Foong, WC, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
7
No studies
1
Included studies
NR
No studies 1 · 12.5%Ungraded 0 · 0%Very low 5 · 62.5%Low 2 · 25%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Pharmacological oral galactagogues compared to placebo or no treatment for increasing breast milk production in mothers of non‐hospitalised term infants
Population: increasing breast milk production in mothers of non‐hospitalised term infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of mothers who continued breastfeeding (exclusive or any) at 3, 4 and 6 months Pharmacological oral galactagogues vs placebo or no treatment | no estimate extracted | NR | No studies |
Infant weight at the end of the study (grams) (in trials where they were only receiving own mother's milk)‐ metoclopramide ( Pharmacological oral galactagogues vs placebo or no treatment | no estimate extracted | 1 study · 20 participants | Low Downgraded: imprecision |
Volume of breast milk at the latest time measured (mL) ‐ domperidone, metoclopramide, sulpiride ( Pharmacological oral galactagogues vs placebo or no treatment | no estimate extracted | 3 studies · 151 participants | Low Downgraded: imprecision |
Adverse effects for the infant or mother ( Pharmacological oral galactagogues vs placebo or no treatment | no estimate extracted | 5 studies · 133 participants | Very low Downgraded: imprecision, inconsistency |
Natural oral galactagogues compared to placebo or no treatment for increasing breast milk production in mothers of non‐hospitalised term infants
Population: increasing breast milk production in mothers of non‐hospitalised term infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of mothers who continued breastfeeding (exclusive or any) at 3, 4 and 6 months Natural oral galactagogues vs placebo or no treatment | no estimate extracted | 1 study · 60 participants | Very low Downgraded: imprecision |
Infant weight (where they were only receiving own mother's milk) at the end of the study (grams) ( Natural oral galactagogues vs placebo or no treatment | no estimate extracted | 3 studies · 275 participants | Very low Downgraded: imprecision, inconsistency |
Volume of breast milk at the latest time measured (mL) ( Natural oral galactagogues vs placebo or no treatment | no estimate extracted | 13 studies · 962 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Adverse effects for the infant or mother Natural oral galactagogues vs placebo or no treatment | no estimate extracted | 7 studies · 10 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |