Relative abundance of Veillonella spp. · Young children with early childhood caries and caries-free controls
Veillonella spp. mean relative abundance was higher in ECC children, without a comparative effect estimate or CI.
Mean relative abundance (%) ECC 3.29 (SD 6.83) vs caries-free 2.13 (SD 2.30)
1 study · 87 participants
GRADE not reported
Meta-Analysis Using NGS Data: The Veillonella Species in Dental Caries. 2022 All outcomesSaliva and supragingival biofilm (pooled) · Overall (all sample types)
MD 2.22 [0.54, 3.90]
6 studies · 319 participants
Very low
MD -1.05 [-7.67, 5.57]
2 studies · 161 participants
GRADE not reported
Show 1 more finding
Overall success (composite of clinical and radiographic success) · Permanent teeth with carious pulp exposure
In partial pulpotomy, MTA had significantly higher success than calcium hydroxide (OR 2.81; ungraded).
Show 2 more findings
Dental caries · children
Maternal smoking during pregnancy was associated with higher odds of dental caries in children (OR 1.78, 95% CI 1.55 to 2.05; ungraded).
Show 11 more findings
OR 1.56 [1.46, 1.67]
2 studies
GRADE not reported
OR 1.68 [1.01, 2.79]
1 study
GRADE not reported
Correlation Between Maternal Smoking During Pregnancy and Dental Caries in Children: A Systematic Review and… 2021 All outcomesCommunity/population-based (multiple countries) · Caries assessment: clinical and radiographic examination
OR 1.56 [1.46, 1.67]
1 study
GRADE not reported
OR 1.61 [1.30, 2.01]
4 studies
GRADE not reported
OR 1.55 [1.45, 1.66]
3 studies
GRADE not reported
OR 1.71 [1.34, 2.16]
3 studies
GRADE not reported
Correlation Between Maternal Smoking During Pregnancy and Dental Caries in Children: A Systematic Review and… 2021 All outcomesCommunity/population-based (multiple countries) · Caries assessment: visual/tactile examination
OR 1.48 [1.15, 1.91]
3 studies
GRADE not reported
OR 1.57 [1.47, 1.67]
6 studies
GRADE not reported
OR 1.84 [1.39, 2.45]
2 studies
GRADE not reported
RR 1.26 [1.07, 1.48]
3 studies
GRADE not reported
OR 1.84 [1.39, 2.45]
2 studies
GRADE not reported
Death (all causes) · people with diabetes and CKD
Sodium‐glucose co‐transporter protein 2 (SGLT2) inhibitors leads to lower all‐cause death median compared with placebo (high certainty).
All‐cause mortality · people with sickle cell disease
AEs · chronic pain (excluding headache) in adults
no estimate extracted
0 studies · 0 participants
GRADE not reported
RR 6 [2.2, 16.4]
1 study · 140 participants
Very low
no estimate extracted
8 studies · 1314 participants
Very low
Reduction in pain intensity · chronic pain (excluding headache) in adults
It is very uncertain whether CBT changes pain intensity (number of people with ≥ 30 % improvement)… compared with TAU (at follow‐up) (very low certainty).
Respiratory‐related hospital admissions · patients with chronic obstructive pulmonary disease
It is very uncertain whether self‐management interventions changes respiratory‐related hospital admissions compared with usual care (very low certainty).
Respiratory‐related mortality · patients with chronic obstructive pulmonary disease
Self‐management interventions showed no clear difference in respiratory‐related mortality compared with usual care (low certainty).
All‐cause mortality · patients with chronic obstructive pulmonary disease
Self‐management interventions showed no clear difference in all‐cause mortality compared with usual care (low certainty).
Hospital admissions · patients with chronic obstructive pulmonary disease
Self‐management interventions showed no clear difference in all‐cause hospital admissions compared with usual care (moderate certainty).
COPD exacerbations · patients with chronic obstructive pulmonary disease
Withdrawals due to adverse events · people with chronic gout
Skim milk enriched with GMP/G600 showed no clear difference in study withdrawals due to adverse events compared with skim milk, plus lactose powder (low certainty).
Joint pain reduction ‐ not reported · people with chronic gout
All‐cause mortality
HbA1c (%)
Health‐related quality of life
HbA1c (%)
All‐cause mortality
0.14 [0, 6.98]
8 studies · 2175 participants
Moderate
Peto OR 1.06 [0.62, 1.82]
14 studies · 6173 participants
Low
Adverse events · high‐grade glioma
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found