Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 17 findings · 8 reviews · Neonatal

No studies found 1 · 5.9%GRADE not reported 3 · 17.6%Very low 1 · 5.9%Low 9 · 52.9%Moderate 1 · 5.9%High 2 · 11.8%

Early vs late continuous positive airway pressure (CPAP)

Use of IPPV before discharge · preterm infants with respiratory distress for initial respiratory support

It is very uncertain whether early changes use of IPPV before discharge compared with late continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

Early vs late continuous positive airway pressure (CPAP)

Failure of treatment ‐ death or intermittent positive‐pressure ventilation (IPPV) before hospital discharge · preterm infants with respiratory distress for initial respiratory support

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up

Cognitive outcome · preterm infants
3 findings from 1 review

Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up

Motor outcome at school age (Griffiths Locomotor, MABC) · preterm infants
2 findings from 1 review

Intervention not reported

Survivors at discharge from hospital without severe IVH, PVL, ROP · preterm infants with low birth weight

The intervention showed no clear difference in survivors at discharge from hospital without severe IVH, PVL, ROP (high certainty).

1 finding from 1 review