Cochrane · systematic review · CD013542

Early full enteral feeding for preterm or low birth weight infants

Walsh, V, Brown, JV, Copperthwaite, BR, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
3
No studies
1
Included studies
NR
No studies 1 · 25%Ungraded 0 · 0%Very low 2 · 50%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Early full enteral feeding compared to delayed or progressive feeding for preterm or low birth weight infants

Population: preterm or low birth weight infants
4 questions
OutcomeEffectEvidenceStatus / GRADE
In hospital rate of weight gain (g/kg/day) until term equivalent
Early full enteral feeding vs delayed or progressive feeding
no estimate extracted2 studies · 236 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
In hospital rate of head circumference growth (cm/week) until term equivalent – not reported
Early full enteral feeding vs delayed or progressive feeding
no estimate extractedNRNo studies
Growth restriction (z‐score of weight) at hospital discharge
Early full enteral feeding vs delayed or progressive feeding
no estimate extracted1 study · 46 participantsLow
Downgraded: risk of bias, imprecision
Necrotising enterocolitis
Early full enteral feeding vs delayed or progressive feeding
RR 0.98 [0.38, 2.54]6 studies · 522 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency