Cochrane · systematic review · CD005495
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants
Orton, J, Doyle, LW, Tripathi, T, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 71.4%Moderate 1 · 14.3%High 1 · 14.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Early developmental intervention programmes compared to standard follow‐up in preterm infants
Population: preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Cognitive outcome in infancy ‐ DQ (Bayley, Griffiths, Brunet‐Leizine) Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up | no estimate extracted | 25 studies · 3132 participants | Low Downgraded: risk of bias, inconsistency, publication bias |
Cognitive outcome at preschool age ‐ IQ (Bayley, Stanford‐Binet, McCarthy, WPPSI‐III) Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up | no estimate extracted | 9 studies · 1524 participants | High |
Cognitive outcome at school age ‐ IQ (WISC, Kaufmann, DAS, WASI‐II) Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up | no estimate extracted | 6 studies · 1453 participants | Low Downgraded: risk of bias, inconsistency |
Motor outcome in infancy (Bayley, Griffiths Locomotor) Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up | no estimate extracted | 23 studies · 2737 participants | Low Downgraded: risk of bias, publication bias |
Motor outcome at preschool age (Griffiths Locomotor, McCarthy, MABC) Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up | no estimate extracted | 3 studies · 264 participants | Moderate Downgraded: imprecision |
Motor outcome at school age (Griffiths Locomotor, MABC) Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up | no estimate extracted | 3 studies · 265 participants | Low Downgraded: risk of bias, imprecision |
Motor outcome at school age (low score on MABC) Summary of findings table ‐ Early developmental intervention programmes vs standard follow‐up | RR 1.04 [0.82, 1.32] | 3 studies · 413 participants | Low Downgraded: risk of bias, imprecision |