Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Carotid artery stenting vs endarterectomy

Death or major or disabling stroke between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or major or disabling stroke between randomisation and 30 days… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke or myocardial infarction between randomisation and 30 days after treatment · people with symptomatic carotid stenosis

Carotid artery stenting leads to higher death or any stroke or myocardial infarction between randomisation… compared with endarterectomy (high certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or any stroke between randomisation and 30 days after treatment compared with endarterectomy (moderate certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke between randomisation and 30 days after treatment or ipsilateral stroke until end of · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or any stroke between randomisation and 30 days after… compared with endarterectomy (moderate certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or major or disabling stroke between randomisation and 30 days after treatment · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or major or disabling stroke between randomisation and 30 days… compared with endarterectomy (moderate certainty).

1 finding from 1 review

Carotid artery stenting vs endarterectomy

Death or any stroke or myocardial infarction between randomisation and 30 days after treatment · asymptomatic carotid stenosis

Carotid artery stenting showed no clear difference in death or any stroke or myocardial infarction between randomisation… compared with endarterectomy (moderate certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) vs supplemental oxygen

Bronchopulmonary dysplasia at 28 days · preterm infants with respiratory distress for initial respiratory support

It is very uncertain whether CPAP changes bronchopulmonary dysplasia (oxygen dependency at 28 days) compared with supplemental oxygen (very low certainty).

1 finding from 1 review

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Clinical cure · women aged 16 and over with uncomplicated vulvovaginal candidiasis

Oral showed no clear difference in clinical cure (short term: 5 to 15 days) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (moderate certainty).

1 finding from 1 review

Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis

Mycological cure · women aged 16 and over with uncomplicated vulvovaginal candidiasis

Oral probably leads to higher mycological cure (short term; 5 to 15 days) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo or no treatment

Neonatal death (baby born alive at any gestation and dies within 28 days) · infants born of women at risk of preterm birth

Neonatal and child outcomes: corticosteroids leads to lower neonatal death (infants born with signs of life who die within the… compared with placebo or no treatment (high certainty).

1 finding from 1 review

Intervention not reported

Time to achieve full enteral feeding (days) · preterm infants with low birth weight

The intervention showed no clear difference in time to achieve full enteral feeding (days) (low certainty).

1 finding from 1 review