Cochrane · systematic review · CD000515
Carotid artery stenting versus endarterectomy for treatment of carotid artery stenosis
Müller, MD, Lyrer, P, Brown, MM, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
StrokeAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
9
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 11.1%Moderate 4 · 44.4%High 4 · 44.4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Carotid artery stenting compared to endarterectomy for symptomatic carotid stenosis
Population: people with symptomatic carotid stenosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or any stroke between randomisation and 30 days after treatment Carotid artery stenting vs endarterectomy | OR 1.7 [1.31, 2.19] | 10 studies · 5396 participants | High |
Death or any stroke between randomisation and 30 days after treatment or ipsilateral stroke until end of Carotid artery stenting vs endarterectomy | OR 1.51 [1.24, 1.85] | 8 studies · 5080 participants | High |
Death or major or disabling stroke between randomisation and 30 days after treatment Carotid artery stenting vs endarterectomy | OR 1.36 [0.97, 1.91] | 7 studies · 4983 participants | High |
Death or any stroke or myocardial infarction between randomisation and 30 days after treatment Carotid artery stenting vs endarterectomy | OR 1.43 [1.14, 1.8] | 6 studies · 4861 participants | High |
Carotid artery stenting compared to endarterectomy for asymptomatic carotid stenosis
Population: people with asymptomatic carotid stenosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or any stroke between randomisation and 30 days after treatment Carotid artery stenting vs endarterectomy | OR 1.72 [1, 2.97] | 7 studies · 3378 participants | Moderate Downgraded: imprecision |
Death or any stroke between randomisation and 30 days after treatment or ipsilateral stroke until end of Carotid artery stenting vs endarterectomy | OR 1.27 [0.87, 1.84] | 6 studies · 3315 participants | Moderate Downgraded: imprecision |
Death or major or disabling stroke between randomisation and 30 days after treatment Carotid artery stenting vs endarterectomy | OR 1.54 [0.39, 6.11] | 2 studies · 2601 participants | Moderate Downgraded: imprecision |
Death or any stroke or myocardial infarction between randomisation and 30 days after treatment Carotid artery stenting vs endarterectomy | OR 1.16 [0.73, 1.85] | 6 studies · 2978 participants | Moderate Downgraded: imprecision |
Carotid artery stenting compared to endarterectomy for prevention of severe restenosis in people with symptomatic or asymptomatic carotid stenosis
Population: people with symptomatic or asymptomatic carotid stenosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severe (≥ 70%) restenosis during Carotid artery stenting vs endarterectomy | OR 1.21 [0.76, 1.93] | 9 studies · 5744 participants | Low Downgraded: inconsistency |