Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis: Clinical cure
Oral showed no clear difference in clinical cure (short term: 5 to 15 days) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis Clinical cure (short term: 5 to 15 days) · women aged 16 and over with uncomplicated vulvovaginal candidiasis Oral showed no clear difference in clinical cure (short term: 5 to 15 days) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (moderate certainty). Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal… (2020) · Cochrane Headline outcomes only | OR 1.14 [0.91, 1.43] | 13 studies · 1859 participants | Moderate |
Oral vs intra‐vaginal antifungal treatment of uncomplicated vulvovaginal candidiasis Clinical cure (long term; 2 to 12 weeks) · women aged 16 and over with uncomplicated vulvovaginal candidiasis Oral showed no clear difference in clinical cure (long term; 2 to 12 weeks) compared with intra‐vaginal antifungal treatment of uncomplicated vulvovaginal… (moderate certainty). Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal… (2020) · Cochrane Headline outcomes only | OR 1.07 [0.77, 1.5] | 9 studies · 1042 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral versus intra‐vaginal imidazole and triazole anti‐fungal treatment of uncomplicated vulvovaginal candidiasis (thrush) 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.