Cochrane · systematic review · CD006212
Vena caval filters for the prevention of pulmonary embolism
Young, T, Sriram, KB · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
VascularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
9
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 10%Very low 0 · 0%Low 0 · 0%Moderate 9 · 90%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Retrievable vena caval filters with anticoagulation compared to anticoagulation for prevention of PE
Population: participants with unprovoked acute symptomatic PE and at high risk for recurrent PEa
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
PE: recurrent fatal and non‐fatal PE, demonstrated by CT, pulmonary angiography or ventilation‐perfusion lung scan (up to 6 months) Retrievable vena caval filters with anticoagulation vs anticoagulation | RR 1.74 [0.52, 5.86] | 1 study · 399 participants | Moderate Downgraded: risk of bias, imprecision |
Mortality (up to 6 months) Retrievable vena caval filters with anticoagulation vs anticoagulation | RR 1.39 [0.74, 2.62] | 1 study · 399 participants | Moderate Downgraded: risk of bias, imprecision |
Symtomatic lower extremity venous thrombosis confirmed by Doppler ultrasound or venography (up to 6 months) Retrievable vena caval filters with anticoagulation vs anticoagulation | RR 0.5 [0.05, 5.44] | 1 study · 399 participants | Moderate Downgraded: risk of bias, imprecision |
Filter‐related complications (up to 6 months) Retrievable vena caval filters with anticoagulation vs anticoagulation | no estimate extracted | 1 study · 399 participants | Ungraded |
Major bleedingc (up to 6 months) Retrievable vena caval filters with anticoagulation vs anticoagulation | RR 0.86 [0.42, 1.77] | 1 study · 399 participants | Moderate Downgraded: risk of bias, imprecision |
Retrievable vena caval filters with anticoagulation compared to anticoagulation for prevention of PE following multiple traumatic injuries
Population: participants who sustained multiple traumatic injuriesa
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Symptomatic PE recurrent; as demonstrated by CT, pulmonary angiography, or post‐mortem, at 90 days Retrievable vena caval filters with anticoagulation vs anticoagulation | no estimate extracted | 1 study · 80 participants | Moderate Downgraded: risk of bias, imprecision |
Mortality from any cause (up to 90 days) Retrievable vena caval filters with anticoagulation vs anticoagulation | no estimate extracted | 1 study · 240 participants | Moderate Downgraded: risk of bias, imprecision |
Lower extremity venous thrombosis confirmed by Doppler ultrasound or venography (at 14 days) Retrievable vena caval filters with anticoagulation vs anticoagulation | no estimate extracted | 1 study · 240 participants | Moderate Downgraded: risk of bias, imprecision |
Filter‐related complications (up to 232 days) Retrievable vena caval filters with anticoagulation vs anticoagulation | no estimate extracted | 1 study · 240 participants | Moderate Downgraded: risk of bias, imprecision |
Major bleedingd (at 90 days) Retrievable vena caval filters with anticoagulation vs anticoagulation | no estimate extracted | 1 study · 240 participants | Moderate Downgraded: risk of bias, imprecision |