Cochrane · systematic review · CD002271
Continuous positive airway pressure (CPAP) for respiratory distress in preterm infants
Ho, JJ, Subramaniam, P, Davis, PG · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 60%Low 1 · 20%Moderate 1 · 20%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
CPAP compared to supplemental oxygen for respiratory distress in preterm infants
Population: respiratory distress in preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Treatment failure (death or use of additional ventilatory support) CPAP vs supplemental oxygen | RR 0.64 [0.5, 0.82] | 5 studies · 322 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Use of assisted ventilation CPAP vs supplemental oxygen | RR 0.72 [0.54, 0.96] | 3 studies · 233 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Mortality CPAP vs supplemental oxygen | RR 0.53 [0.34, 0.83] | 5 studies · 322 participants | Moderate Downgraded: imprecision |
Pneumothorax occurring after allocation CPAP vs supplemental oxygen | RR 2.91 [1.38, 6.13] | 4 studies · 270 participants | Low Downgraded: imprecision |
Bronchopulmonary dysplasia (oxygen dependency at 28 days) CPAP vs supplemental oxygen | RR 1.04 [0.35, 3.13] | 2 studies · 209 participants | Very low Downgraded: imprecision |