Dental caries in children · Mother-child pairs
In one cross-sectional study, higher maternal allostatic load was associated with child dental caries experience and with health-related maternal care-taking behaviours; not pooled (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with previously unrestored, vital carious lesions in primary teeth (no pulp therapy); aged 1.5-11 years
High-viscosity GIC had a wide annual failure rate (2.9-25.6%) and was outperformed by compomer/composite in some trials (3 RCTs); low quality of evidence (ungraded).
1 finding from 1 review
Dental caries · Adults (≥18 years)
After adjustment for confounders, obesity/overweight was not associated with dental caries (OR 1.00, 95% CI 0.89 to 1.12; ungraded).
9 findings from 1 review
Multimorbidity patterns of dental caries and obesity/overweight among adults: a systematic review and meta-analysis. 2025 All outcomesPopulation-based cross-sectional studies; adults ≥18 years; 6 countries (Turkey, Portugal, China, Japan, Saudi Arabia, Israel, South Korea) · By confounder adjustment: adjusted
OR 1.00 [0.89, 1.12]
Studies not reported
GRADE not reported
Multimorbidity patterns of dental caries and obesity/overweight among adults: a systematic review and meta-analysis. 2025 All outcomesPopulation-based cross-sectional studies; adults ≥18 years; 6 countries (Turkey, Portugal, China, Japan, Saudi Arabia, Israel, South Korea) · By region: West Asia
OR 1.23 [0.96, 1.50]
Studies not reported
GRADE not reported
Multimorbidity patterns of dental caries and obesity/overweight among adults: a systematic review and meta-analysis. 2025 All outcomesPopulation-based cross-sectional studies; adults ≥18 years; 6 countries (Turkey, Portugal, China, Japan, Saudi Arabia, Israel, South Korea) · By BMI classification: overweight (vs study-defined non-overweight: normal or low weight)
OR 0.99 [0.98, 1.00]
Studies not reported
GRADE not reported
Show 6 more findings
Prevalence and severity of oral and TMJ diseases/conditions (periodontal status and dental caries) · Children and adolescents with juvenile idiopathic arthritis (JIA)
Some studies suggested greater JIA disease activity/severity (and certain medications) was associated with worse periodontal and caries outcomes, but small samples meant no solid conclusion could be drawn (ungraded).
1 finding from 1 review
Treatment failure (annual failure rate) · Children with carious primary teeth treated by atraumatic restorative treatment (hand-instrument caries removal), no pulp therapy
ART restorations (mainly GIC) had a wide annual failure rate (1.2-37.1%) across 10 RCTs, with technique affecting survival; low to unclear quality of evidence (ungraded).
1 finding from 1 review
Odds of higher caries (DMFT) category · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
In the adjusted ordinal model geographical location was not independently significant for DMFT category (OR 0.57, 95% CI 0.24 to 1.35); not GRADE-rated.
1 finding from 1 review
High salivary P. gingivalis (over 10^4 CFU/ml) · adults
Periodontitis was associated with higher odds of detectable high-level salivary P. gingivalis (OR 3.38).
1 finding from 1 review
OR 3.38 [1.46, 7.83]
2 studies
GRADE not reported
High salivary S. mutans (over 10^4 CFU/ml) · adults
Salivary S. mutans showed a non-significant declining trend with periodontitis (OR 0.82).
1 finding from 1 review
OR 0.82 [0.44, 1.51]
2 studies
GRADE not reported
High salivary S. mutans (over 10^4 CFU/ml) · Periodontitis patients
High-level S. mutans did not change significantly after periodontal therapy (OR 1.54).
1 finding from 1 review
Dental caries · Children (deciduous and/or permanent dentition) in low- and middle-income countries
High SES showed no significant association with dental caries (OR 1.03, 95% CI 0.81 to 1.31; 5 studies; not GRADE-rated).
1 finding from 1 review
Dental caries (association with secondary/higher maternal education) · Children (deciduous and/or permanent dentition) in low- and middle-income countries
Secondary/higher maternal education showed no significant association with dental caries (OR 0.96, 95% CI 0.64 to 1.44; 7 studies; not GRADE-rated).
1 finding from 1 review
Secondary/higher maternal education prevalence (among children with caries) · Children with dental caries (deciduous and/or permanent dentition) in low- and middle-income countries
About 45% of children with caries in LMICs had mothers with secondary or higher education (pooled prevalence 0.450, 95% CI 0.330 to 0.572; 7 studies; not GRADE-rated).
1 finding from 1 review
High SES prevalence (among children with caries) · Children with dental caries (deciduous and/or permanent dentition) in low- and middle-income countries
About 25% of children with caries in LMICs were of high SES (pooled prevalence 0.245, 95% CI 0.162 to 0.339; 5 studies; not GRADE-rated).
1 finding from 1 review
High density lipoprotein · Adults (general population)
Meta-analysis of randomised trials of vitamin D supplementation for High density lipoprotein: WMD -0.14 (95% CI -0.99 to 0.71), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
1 finding from 1 review
WMD -0.14 [-0.99, 0.71]
8 studies
GRADE not reported
Early childhood caries (ECC) · Healthy children under 6 years of age (6 months to 6 years); preschool children
After excluding an extreme outlier (Alhabdan 2018), the association between low brushing frequency and ECC remained statistically significant (pooled OR approximately 2.0, p=0.003; I2=87.5%); the exact estimate and its CI were not reported; ungraded.
2 findings from 1 review
Caries experience (mean DMFT) · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)
Mean DMFT tended to increase with unemployment rate (low 1.23, medium 2.08, high 2.38; ANOVA p<.05); descriptive country-level means only, not meta-analyzed or GRADE-rated.
3 findings from 1 review
Oral health-related quality of life · people aged 60 years and older living in the community
OHRQoL did not differ significantly by country-level periodontal disease prevalence; no pooled estimate was reported in the text (ungraded).
1 finding from 1 review
Oral health-related quality of life · people aged 60 years and older living in the community
Community-dwelling older adults in higher-income countries had better OHRQoL than those in lower-income countries (77.9, 95% CI 70.2 to 85.6 vs 66.9, 95% CI 56.7 to 77.0); the difference by income was statistically significant (ungraded).
2 findings from 1 review
MEAN 77.9 [70.2, 85.6]
Studies not reported
GRADE not reported
MEAN 66.9 [56.7, 77.0]
Studies not reported
GRADE not reported
Oral health-related quality of life · people aged 60 years and older living in the community
Older adults in countries with relative income equality (low Gini index) had markedly higher OHRQoL (91.3, 95% CI 90.0 to 92.6) than those in less equal countries; the difference by Gini index was statistically significant (ungraded).
4 findings from 1 review
Show 1 more finding
MEAN 81.2 [75.3, 88.3]
Studies not reported
GRADE not reported
Oral health-related quality of life · people aged 60 years and older living in the community
Older adults in higher-HDI countries had better OHRQoL (high 79.9, 95% CI 74.4 to 85.5; very high 78.4, 95% CI 71.1 to 85.8) than those in medium-HDI countries (63.5, 95% CI 54.3 to 72.7); the difference by HDI was statistically significant (ungraded).
3 findings from 1 review
MEAN 79.9 [74.4, 85.5]
Studies not reported
GRADE not reported
MEAN 63.5 [54.3, 72.7]
Studies not reported
GRADE not reported
MEAN 78.4 [71.1, 85.8]
Studies not reported
GRADE not reported