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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Supervised exercise therapy following vascular intervention vs vascular intervention alone
Quality of life SF‐36 Physical component absolute score · people with symptomatic peripheral arterial disease§
Effects of additional exercise therapy after a successful vascular intervention for people with symptomatic… (2024) · Cochrane
no estimate extracted2 studies · 105 participantsVery low
Supervised exercise therapy following vascular intervention vs vascular intervention alone
Reintervention · people with symptomatic peripheral arterial disease§
Effects of additional exercise therapy after a successful vascular intervention for people with symptomatic… (2024) · Cochrane
OR 0.91 [0.23, 3.65]5 studies · 252 participantsVery low
Summary of findings table ‐ Purse‐string skin closure vs linear skin closure
Surgical site infection · people undergoing stoma reversal
Purse‐string skin closure versus linear skin closure in people undergoing stoma reversal (2024) · Cochrane
OR 0.17 [0.09, 0.29]9 studies · 757 participantsModerate
Summary of findings table ‐ Purse‐string skin closure vs linear skin closure
Participant satisfaction (very satisfied or satisfied) · people undergoing stoma reversal
Purse‐string skin closure versus linear skin closure in people undergoing stoma reversal (2024) · Cochrane
OR 20.11 [1.09, 369.88]2 studies · 122 participantsLow
Summary of findings table ‐ Purse‐string skin closure vs linear skin closure
Incisional hernia · people undergoing stoma reversal
Purse‐string skin closure versus linear skin closure in people undergoing stoma reversal (2024) · Cochrane
OR 0.51 [0.07, 3.7]4 studies · 297 participantsVery low
Summary of findings table ‐ Purse‐string skin closure vs linear skin closure
Operative time · people undergoing stoma reversal
Purse‐string skin closure versus linear skin closure in people undergoing stoma reversal (2024) · Cochrane
no estimate extracted6 studies · 460 participantsVery low
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
Daily fluid balance in millilitres (measured from admission to discharge) · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
no estimate extracted2 studies · 169 participantsVery low
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
Net weight loss (measured from admission to discharge) · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
no estimate extracted5 studies · 497 participantsVery low
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
All‐cause mortality (from admission to discharge) · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
RR 1.53 [0.81, 2.9]5 studies · 530 participantsLow
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
Cardiovascular mortality ‐ not measured · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
Length of hospital stay (from admission to discharge) · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
no estimate extracted4 studies · 211 participantsVery low
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
Readmission to hospital following discharge · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
RR 0.85 [0.63, 1.16]3 studies · 400 participantsLow
Summary of findings table ‐ Continuous infusion of intravenous loop diuretics vs bolus injection of intravenous loop diuretics
Acute kidney injury (adverse event) (from admission to discharge) · adults (aged greater than 18 years) with acute heart failure
Continuous infusion versus bolus injection of loop diuretics for acute heart failure (2024) · Cochrane
RR 1.02 [0.7, 1.49]3 studies · 491 participantsLow
Zinc vs placebo
Proportion of participants developing a cold Duration of · adults and children without colds
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted9 studies · 1449 participantsLow
Zinc vs placebo
Proportion with improved global symptom severity Duration of · adults and children with colds and/or upper respiratory infections
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted1 study · 114 participantsLow
Zinc vs placebo
Risk of adverse events, including those that may be due to zinc supplements Duration of · adults and children with colds and/or upper respiratory infections
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted16 studies · 2084 participantsModerate
Zinc vs placebo
Risk of serious adverse events, including those that may be complications of the common cold · adults and children with colds and/or upper respiratory infections
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extractedNRNo studies
Zinc vs placebo
Mean number of colds developed Duration of · adults and children without colds
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted2 studies · 1284 participantsLow
Zinc vs placebo
Mean duration of colds in days Duration of · adults and children without colds
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted3 studies · 740 participantsModerate
Zinc vs placebo
Standardised mean global symptom severity Duration of · adults and children without colds
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted2 studies · 101 participantsLow
Zinc vs placebo
Risk of adverse events, including those that may be due to zinc supplements Duration of · adults and children without colds
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted7 studies · 1517 participantsVery low
Zinc vs placebo
Risk of serious adverse events, including those that may be complications of the common cold Duration of · adults and children without colds
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted3 studies · 1563 participantsLow
Zinc vs placebo
Mean duration of colds in days Duration of · adults and children with colds and/or upper respiratory infections
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted8 studies · 972 participantsLow
Zinc vs placebo
Risk of continuing colds at study end Duration of · adults and children with colds and/or upper respiratory infections
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted5 studies · 357 participantsVery low
Zinc vs placebo
Standardised mean global symptom severity Duration of · adults and children with colds and/or upper respiratory infections
Zinc for prevention and treatment of the common cold (2024) · Cochrane
no estimate extracted2 studies · 261 participantsVery low
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
Proportion of participants without successful treatment at longest · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
RR 1.05 [0.66, 1.66]3 studies · 340 participantsVery low
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
All‐cause mortality (or overall survival) ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
Proportion of participants without successful treatment at 1 year · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
RR 0.65 [0.32, 1.31]1 study · 99 participantsVery low
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
Proportion of participants with ≥ 1 serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
Health‐related quality of life ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
All‐cause mortality (or overall survival) ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
RR 0.71 [0.34, 1.46]1 study · 214 participantsVery low
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
Quality of life · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extracted1 study · 214 participantsVery low
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
Quality of life · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extracted1 study · 214 participantsVery low
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
All‐cause mortality (or overall survival) ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
Proportion of participants without successful treatment ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
RR 0.34 [0.04, 3.15]1 study · 91 participantsVery low
Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation
Health‐related quality of life ‐ not reported · adults with biliary sphincter of Oddi dysfunction
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs placebo or no intervention
All‐cause mortality · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 0.15 [0.01, 2.83]1 study · 782 participantsLow
Summary of findings table ‐ Antibiotics vs other antibiotics
Clinical diagnosis of leptospirosis regardless of laboratory confirmation · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 4.18 [0.94, 18.66]1 study · 137 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Clinical diagnosis of leptospirosis confirmed by laboratory diagnosis · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 4.18 [0.94, 18.66]1 study · 137 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Serious adverse events ‐ not reported · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs other antibiotics
Quality of life ‐ not reported · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs other antibiotics
Non‐serious adverse events · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 1.12 [0.36, 3.48]1 study · 137 participantsVery low
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Laboratory‐confirmed leptospirosis · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 0.56 [0.25, 1.26]5 studies · 2593 participantsVery low
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Clinical diagnosis of infection regardless of laboratory confirmed · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 0.76 [0.53, 1.08]4 studies · 1653 participantsLow
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Clinical diagnosis confirmed by laboratory diagnosis · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 0.57 [0.26, 1.26]4 studies · 1653 participantsLow