Cochrane · systematic review · CD014944
Endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction
Naing, C, Ni, H, Aung, HH, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
16
current version
GRADE rated
6
No studies
10
Included studies
NR
No studies 10 · 62.5%Ungraded 0 · 0%Very low 6 · 37.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings table ‐ Endoscopic sphincterotomy compared with sham treatment for adults with biliary sphincter of Oddi dysfunction
Population: adults with biliary sphincter of Oddi dysfunction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of participants without successful treatment at longest Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment | RR 1.05 [0.66, 1.66] | 3 studies · 340 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Proportion of participants with ≥ 1 serious adverse events at 1 year Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment | RR 0.71 [0.34, 1.46] | 1 study · 214 participants | Very low Downgraded: imprecision |
Quality of life Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment | no estimate extracted | 1 study · 214 participants | Very low Downgraded: imprecision |
Quality of life Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment | no estimate extracted | 1 study · 214 participants | Very low Downgraded: imprecision |
All‐cause mortality (or overall survival) ‐ not reported Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment | no estimate extracted | NR | No studies |
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported Summary of findings table ‐ Endoscopic sphincterotomy vs sham treatment | no estimate extracted | NR | No studies |
Summary of findings table ‐ Endoscopic sphincterotomy compared with endoscopic papillary balloon dilation for adults with biliary sphincter of Oddi dysfunction
Population: adults with biliary sphincter of Oddi dysfunction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of participants without successful treatment ‐ not reported Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation | no estimate extracted | NR | No studies |
Proportion of participants with ≥ 1 serious adverse events at 1 year Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation | RR 0.34 [0.04, 3.15] | 1 study · 91 participants | Very low Downgraded: risk of bias, imprecision |
Health‐related quality of life ‐ not reported Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation | no estimate extracted | NR | No studies |
All‐cause mortality (or overall survival) ‐ not reported Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation | no estimate extracted | NR | No studies |
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation | no estimate extracted | NR | No studies |
Summary of findings table ‐ Biliary endoscopic sphincterotomy compared with dual endoscopic sphincterotomy for adults with biliary sphincter of Oddi dysfunction
Population: adults with biliary sphincter of Oddi dysfunction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Proportion of participants without successful treatment at 1 year Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy | RR 0.65 [0.32, 1.31] | 1 study · 99 participants | Very low Downgraded: risk of bias, imprecision |
Proportion of participants with ≥ 1 serious adverse events ‐ not reported Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy | no estimate extracted | NR | No studies |
Health‐related quality of life ‐ not reported Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy | no estimate extracted | NR | No studies |
All‐cause mortality (or overall survival) ‐ not reported Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy | no estimate extracted | NR | No studies |
Proportion of participants with ≥ 1 non‐serious adverse events ‐ not reported Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy | no estimate extracted | NR | No studies |