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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Serious adverse events ‐ not reported · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Quality of life ‐ not reported · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Non‐serious adverse events · farmworkers, soldiers, and people in endemic areas
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 10.13 [2.4, 42.71]3 studies · 1909 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
All‐cause mortality ‐ not reported · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs other antibiotics
Laboratory‐confirmed leptospirosis · farmworkers
Antibiotic prophylaxis for leptospirosis (2024) · Cochrane
RR 1.53 [0.53, 4.45]1 study · 137 participantsVery low
Summary of findings table ‐ Antibiotics vs placebo or no intervention
All‐cause mortality · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 1.57 [0.65, 3.79]3 studies · 367 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Adverse events considered non‐serious (penicillin versus cefotaxime) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 3.03 [0.13, 73.47]1 study · 175 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Adverse events considered non‐serious (penicillin versus doxycycline) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 2.8 [0.12, 67.66]1 study · 168 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Adverse events considered non‐serious (penicillin versus chloramphenicol) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 0.74 [0.15, 3.67]1 study · 52 participantsVery low
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Serious adverse event ‐ not reported · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Antibiotics vs placebo or no intervention
Adverse events considered non‐serious · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 1.05 [0.35, 3.17]2 studies · 162 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
All‐cause mortality (penicillin versus a cephalosporin (cefotaxime or ceftriaxone)) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 1.38 [0.47, 4.04]2 studies · 348 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
All‐cause mortality (penicillin versus doxycycline) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 0.93 [0.13, 6.46]1 study · 168 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
All‐cause mortality (a cephalosporin (cefotaxime) versus doxycycline) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 0.18 [0.01, 3.78]1 study · 169 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Serious adverse events (nosocomial infection) (penicillin versus cefotaxime) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 1.01 [0.15, 7.02]1 study · 175 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Serious adverse events (nosocomial infection) (penicillin versus doxycycline) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 0.62 [0.11, 3.62]1 study · 168 participantsVery low
Summary of findings table ‐ Antibiotics vs other antibiotics
Serious adverse events (nosocomial infection) (doxycycline versus cefotaxime) · people with leptospirosis
Antibiotics for treatment of leptospirosis (2024) · Cochrane
RR 1.01 [0.15, 7.02]1 study · 175 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy
Health‐related quality of life ‐ not reported · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy
Incidence of anastomotic leakage · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 0.34 [0.05, 2.08]2 studies · 213 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy
Changes in body weight from baseline ‐ not reported · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy
Incidence of bile reflux · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 10.74 [3.52, 32.76]1 study · 108 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy
Incidence of remnant gastritis · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 1.18 [0.69, 2.01]3 studies · 361 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy
Incidence of oesophagitis · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 0.82 [0.53, 1.26]3 studies · 361 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy
Major postoperative complications · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 0.98 [0.24, 4.05]2 studies · 282 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy
Incidence of anastomotic leakage · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 0.64 [0.29, 1.44]3 studies · 615 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy
Changes in body weight from baseline · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
no estimate extracted2 studies · 233 participantsLow
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy
Incidence of bile reflux · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 0.67 [0.55, 0.83]1 study · 141 participantsLow
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy
Incidence of remnant gastritis · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 0.27 [0.01, 5.06]2 studies · 265 participantsVery low
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Billroth II reconstruction after distal gastrectomy
Incidence of oesophagitis ‐ not reported · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy
Health‐related quality of life ‐ not reported · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
no estimate extractedNRNo studies
Summary of findings table ‐ Uncut Roux‐en‐Y reconstruction vs Roux‐en‐Y reconstruction after distal gastrectomy
Major postoperative complications · people undergoing distal gastrectomy for gastric cancer
Uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer (2024) · Cochrane
RR 4.74 [0.23, 97.08]2 studies · 256 participantsVery low
Intervention NR
Transmission‐related outcomes: cases‐ number or proportion of cases
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Intervention NR
Transmission‐related outcomes: cases ‐ risk of infection
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRVery low
Intervention NR
Transmission‐related outcomes: cases‐ number or proportion of cases
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Intervention NR
Intended and unintended consequences: social and institutional consequences ‐ days of absences avoided
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Intervention NR
PPV
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRVery low
Intervention NR
Proportion of cases detected
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRVery low
Intervention NR
Onward transmission (secondary and tertiary transmission)
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRVery low
Intervention NR
Transmission‐related outcomes: cases ‐ risk of infection
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRVery low
Intervention NR
Transmission‐related outcomes: cases ‐ number or proportion of cases
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Intervention NR
Transmission‐related outcomes: cases ‐ epidemic progression
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRLow
Intervention NR
Transmission‐related outcomes: cases ‐ risk of infection
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRVery low
Intervention NR
Transmission‐related outcomes: cases: risk of infection
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRVery low
Intervention NR
Transmission‐related outcomes: deaths ‐ number and proportion of deaths
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Intervention NR
Transmission‐related outcomes: hospitalization ‐ number or proportion of hospital admissions
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Intervention NR
Transmission‐related outcomes: hospitalization ‐ Number or proportion of hospital admissions
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Intervention NR
Transmission‐related outcomes: cases ‐ number or proportion of cases
Measures implemented in the school setting to contain the COVID‐19 pandemic (2024) · Cochrane
no estimate extractedNRModerate
Antibiotics vs surgery
Mortality · adults with uncomplicated appendicitis
Appendectomy versus antibiotic treatment for acute appendicitis (2024) · Cochrane
OR 0.51 [0.05, 4.95]5 studies · 2377 participantsVery low
Antibiotics vs surgery
Success of treatment · adults with uncomplicated appendicitis
Appendectomy versus antibiotic treatment for acute appendicitis (2024) · Cochrane
RR 0.91 [0.87, 0.96]7 studies · 2471 participantsLow
Antibiotics vs surgery
Appendectomy in the antibiotic group · adults with uncomplicated appendicitis
Appendectomy versus antibiotic treatment for acute appendicitis (2024) · Cochrane
no estimate extracted9 studies · 1396 participantsVery low