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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Prebiotics and anti‐inflammatory therapy vs anti‐inflammatory therapy
Withdrawals due to adverse events · people with mild‐to‐moderate ulcerative colitis based on Truelove and Witts criteria
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs placebo
Clinical relapse (6 months) · people with histologically confirmed diagnosis of ulcerative colitis in remission
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 1.36 [0.79, 2.31]1 study · 89 participantsLow
Prebiotics vs placebo
Clinical improvement (partial Mayo score) (60 days) · people with histologically confirmed diagnosis of ulcerative colitis in remission
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extracted1 study · 30 participantsVery low
Prebiotics vs placebo
Quality of life (IBDQ) (60 days) · people with histologically confirmed diagnosis of ulcerative colitis in remission
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extracted1 study · 30 participantsVery low
Prebiotics vs placebo
Total adverse events (6 months) · people with histologically confirmed diagnosis of ulcerative colitis in remission
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 1.68 [1.18, 2.4]1 study · 89 participantsLow
Prebiotics vs placebo
Clinical improvement (Rachmilewitz index) (14 days) · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extracted1 study · 15 participantsVery low
Prebiotics vs placebo
Withdrawals due to adverse events (60 days to 6 months) · people with histologically confirmed diagnosis of ulcerative colitis in remission
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 2.57 [1.15, 5.73]2 studies · 125 participantsVery low
Prebiotics vs probiotics
Clinical relapse (4 weeks) · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs probiotics
Clinical improvement · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs probiotics
Quality of life (IBDQ) (4 weeks) · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extracted1 study · 62 participantsVery low
Prebiotics vs probiotics
Total adverse events · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs probiotics
Withdrawals due to adverse events (4 weeks) · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 1 [0.44, 2.26]1 study · 80 participantsVery low
Prebiotics vs synbiotics
Clinical relapse (4 weeks) · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs synbiotics
Clinical improvement · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs synbiotics
Quality of life (IBDQ) (4 weeks) · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extracted1 study · 63 participantsVery low
Prebiotics vs synbiotics
Total adverse events · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs placebo
Quality of life (IBDQ) (2 or 3 months) · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extracted1 study · 8 participantsVery low
Prebiotics vs synbiotics
Withdrawals due to adverse events (4 weeks) · people in remission or with mildly activeulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 1.13 [0.48, 2.62]1 study · 80 participantsVery low
Prebiotics vs placebo
Total adverse events · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Prebiotics vs placebo
Withdrawals due to adverse events (14 days to 2 or 3 months) · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 2.73 [0.51, 14.55]2 studies · 31 participantsVery low
Inulin and oligofructose 15 g vs inulin and oligofructose 7.5 g daily
Clinical remission (9 weeks) · people with mild to moderately active ulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 4.27 [1.07, 16.96]1 study · 31 participantsVery low
Inulin and oligofructose 15 g vs inulin and oligofructose 7.5 g daily
Clinical improvement (Mayo score) (9 weeks) · people with mild to moderately active ulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 2.67 [1.06, 6.7]1 study · 31 participantsVery low
Inulin and oligofructose 15 g vs inulin and oligofructose 7.5 g daily
Quality of life · people with mild to moderately active ulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
no estimate extractedNRNo studies
Inulin and oligofructose 15 g vs inulin and oligofructose 7.5 g daily
Total adverse events (9 weeks) · people with mild to moderately active ulcerative colitis
Prebiotics for induction and maintenance of remission in ulcerative colitis (2024) · Cochrane
RR 1.71 [0.72, 4.06]1 study · 31 participantsVery low
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
Rates of symptomatic PCR‐positive SARS‐CoV‐2 infection (over 13‐week · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
RR 1.28 [0.74, 2.21]1 study · 24027 participantsVery low
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
Rates of any PCR‐positive SARS‐CoV‐2 infection (over 13‐week · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
RR 1.35 [0.82, 2.21]1 study · 24027 participantsVery low
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
SARS‐CoV‐2‐related mortality · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
no estimate extractedNRNo studies
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
Adverse events · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
no estimate extractedNRNo studies
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
COVID‐related absenteeism from work Days absent per 1000 working days (over 13‐week · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
RR 0.83 [0.55, 1.25]1 study · 24027 participantsLow
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
All‐cause mortality · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
no estimate extractedNRNo studies
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
Quality of life · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
no estimate extractedNRNo studies
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
Hospitalisation · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
no estimate extractedNRNo studies
Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2‐positive person
Adherence to strategies: uptake of rapid antigen test (over 13‐week · school staff
Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings (2024) · Cochrane
no estimate extracted1 study · 253 participantsUngraded
Respiratory syncytial virus vaccine vs placebo
Infant hospitalisation with laboratory‐confirmed RSV disease · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
RR 0.5 [0.31, 0.82]4 studies · 12216 participantsHigh
Respiratory syncytial virus vaccine vs placebo
Infant hospitalisation with clinically confirmed RSV disease · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
no estimate extractedNRNo studies
Respiratory syncytial virus vaccine vs placebo
Intrauterine growth restriction · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
RR 1.32 [0.75, 2.33]4 studies · 12545 participantsModerate
Respiratory syncytial virus vaccine vs placebo
Stillbirth · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
RR 0.81 [0.38, 1.72]5 studies · 12652 participantsLow
Respiratory syncytial virus vaccine vs placebo
Maternal death · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
RR 3 [0.12, 73.5]3 studies · 7977 participantsLow
Respiratory syncytial virus vaccine vs placebo
Preterm birth · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
RR 1.16 [0.99, 1.36]6 studies · 17560 participantsVery low
Respiratory syncytial virus vaccine vs placebo
Congenital abnormalities · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
RR 0.96 [0.88, 1.04]4 studies · 12304 participantsHigh
Respiratory syncytial virus vaccine vs placebo
Infant death · pregnant woman
Respiratory syncytial virus vaccination during pregnancy for improving infant outcomes (2024) · Cochrane
RR 0.81 [0.36, 1.81]6 studies · 17589 participantsVery low
Full‐face filtering masks vs no respiratory protection
Reduction in exposure to asbestos · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Powered air‐purifying respirators vs no respiratory protection
Asbestos concentration reduction · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRModerate
Powered air‐purifying respirators vs no respiratory protection
Asbestos exposure after doffing · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Powered air‐purifying respirators vs no respiratory protection
Donning and doffing errors · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
Powered air‐purifying respirators vs no respiratory protection
Adverse effects · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
One type of coverall vs another type of coverall
Asbestos concentration · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
One type of coverall vs another type of coverall
Asbestos concentration after doffing · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
One type of coverall vs another type of coverall
Donning and doffing errors · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extractedNRNo studies
One type of coverall vs another type of coverall
Adverse effects: core body temperature (change from before to after work) · asbestos workers
Personal protective equipment for preventing asbestos exposure in workers (2024) · Cochrane
no estimate extracted1 study · 11 participantsLow